167016-72-0Relevant articles and documents
The effect of N-methylation on transition state mimetic inhibitors of the Plasmodium protease, plasmepsin v
Gazdik, Michelle,O'Neill, Matthew T.,Lopaticki, Sash,Lowes, Kym N.,Smith, Brian J.,Cowman, Alan F.,Boddey, Justin A.,Sleebs, Brad E.
, p. 437 - 443 (2015/03/18)
N-Methylation of the N-Cα peptide bond is a known strategy to overcome the liabilities inherently associated with peptide-like molecules. Here, we apply this strategy to transition state mimetics that are potent inhibitors of the malarial protease, plasme
