16713-88-5

Basic information

• Product Name: 1,2-O-isopropylidene-3-O-tosyl-α-D-xylopentofuranose
• Synonyms: 1,2-O-isopropylidene-3-O-tosyl-α-D-xylopentofuranose
• CAS NO: 16713-88-5
• Molecular Weight: 344.386
• Mol File: 16713-88-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1,2-O-isopropylidene-3-O-tosyl-α-D-xylopentofuranose(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-O-isopropylidene-3-O-tosyl-α-D-xylopentofuranose(16713-88-5)
• EPA Substance Registry System: 1,2-O-isopropylidene-3-O-tosyl-α-D-xylopentofuranose(16713-88-5)

Safety Data

• Hazardous Substances Data: 16713-88-5(Hazardous Substances Data)

Upstream product

• 70580-81-3 5-O-benzoyl-1,2-O-isopropylidene-3-O-paratoluenesulfonyl-α-D-xylofuranose 
• 18016-89-2 1,2-O-isopropylidene-3-O-p-toluenesulfonyl-5-O-trityl-β-D-xylofuranose 
• 98-59-9 p-toluenesulfonyl chloride 
• 20031-21-4 1,2-O-isopropylidene-α-D-xylose 
• 5432-33-7 3-hydroxy-5-O-carboxymethyl-1,2-O-(1-methylethylidene)-α-D-xylofuranoside 
• 74580-94-2 1,2-O-isopropylidene-5-O-(methoxycarbonyl)-3-O-tosyl-α-D-xylofuranose 

Downstream Products

• 1071571-99-7 methyl-[O⁵-methyl-O³-(toluene-4-sulfonyl)-α-D-xylofuranoside] 
• 16713-89-6 O¹,O²-isopropylidene-O³-(toluene-4-sulfonyl)-5-deoxy-α-D-xylofuranose 
• 74581-00-3 Acetic acid (2R,3R,4S,5R)-2-acetoxy-5-acetoxymethyl-4-(toluene-4-sulfonyloxy)-tetrahydro-furan-3-yl ester 
• 74580-99-7 Acetic acid (2S,3R,4S,5R)-2-acetoxy-5-acetoxymethyl-4-(toluene-4-sulfonyloxy)-tetrahydro-furan-3-yl ester 
• 29873-56-1 5-deoxy-5-iodo-1,2-O-isopropylidene-3-O-p-tolylsulfonyl-α-D-xylofuranose 
• 74580-97-5 O⁵-acetyl-O¹,O²-isopropylidene-O³-(toluene-4-sulfonyl)-α-D-xylofuranose 
• 111730-10-0 1,2-O-isopropylidene-3-O-tosyl-5-O-methyl-α-D-xylopentofuranose 

Relevant articles and documents

Selective deprotection of terminal isopropylidene acetals and trityl ethers using HClO4 supported on silica gel

Terminal isopropylidene acetals are selectively cleaved to the corresponding 1,2-diols in good to excellent yields in 6-24 h at room temperature by using the 'HClO4?SiO2' reagent system. Likewise, trityl ethers are readily cleaved to the corresponding alcohols in good to excellent yields within 2-3 h at room temperature. Work-up involves merely filtration of the reagent followed by purification of the crude product.

A mild and selective cleavage of trityl ethers by CBr4-MeOH

Trityl ethers are selectively deprotected to the corresponding alcohols in high yields by CBr4 in refluxing methanol under neutral reaction conditions. Other hydroxyl protecting groups like isopropylidene, allyl, benzyl, acetyl, benzoyl, methyl