16714-27-5

Basic information

• Product Name: Methanone, (2-azidophenyl)phenyl-
• CAS NO: 16714-27-5
• Molecular Formula: C13H9N3O
• Molecular Weight: 223.234
• Mol File: 16714-27-5.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Methanone, (2-azidophenyl)phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanone, (2-azidophenyl)phenyl-(16714-27-5)
• EPA Substance Registry System: Methanone, (2-azidophenyl)phenyl-(16714-27-5)

Safety Data

• Hazardous Substances Data: 16714-27-5(Hazardous Substances Data)

Upstream product

• 36367-99-4 2-Diazobenzophenon-Kation 
• 100-58-3 phenylmagnesium bromide 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 

Downstream Products

• 65245-70-7 C₂₀H₁₇N₅O 
• 82980-00-5 2-azidobenzophenone (Z)-oxime 
• 5176-14-7 3-phenyl-2,1-benzoxazole 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 54567-10-1 N-(2-benzoylphenyl)-formamide 
• 85-99-4 2-acetamidobenzophenone 
• 1228190-95-1 C₁₄H₁₂N₄O 
• 578-95-0 10H-acridin-9-one 
• 1395896-91-9 phenyl [2-(4-phenyl-1H-1,2,3-triazol-1-yl)phenyl] ketone 
• 274917-70-3 2-azido-α-phenylbenzyl alcohol 
• 52744-72-6 (2-aminophenyl)diphenylmethanol 

Relevant articles and documents

Carbon isotope labeling of carbamates by late-stage [11C], [13C] and [14C]carbon dioxide incorporation

A general procedure for the late-stage [11C], [13C] and [14C]carbon isotope labeling of cyclic carbamates is reported. This protocol allows the incorporation of carbon dioxide, the primary source of carbon-14 and carbon-11 radioisotopes, in a direct, cost-effective and sustainable manner. A disconnection/reconnection strategy, involving ring opening/isotopic closure, was also implemented.

Compound and application of compound to treating colon cancer

The invention discloses a compound and application of the compound to treating the colon cancer. The structural formula of the compound is shown in the formula I, wherein R1, R2, R3 and R4 in the formula I are respectively independently chosen from alkyl groups and alkoxy groups, the number of hydrogen atoms, halogen, nitro and carbon atoms in the alkyl group is 1-6, the number of carbon atoms in the alkoxy group is 1-6, R5 is chosen from nitro and -NR6R7, wherein R6 and R7 are respectively independently the hydrogen atom or CH2Ar, the Ar represents a phenyl group or an aryl group, the para-position of the aryl group is substituted by R8, the aryl group is a phenyl group, the R8 is an alkoxy group or the following shown groups, and the number of halogen, hydroxyl and carbon atoms in the R8 is 1-6. The compound also has an obvious effect on inhibiting a tumor sphere from a cancer patient with the colon cancer. In addition, the compound also has an obvious effect on inhibiting the migration and the moving ability of a colon cancer cell line. A novel medicine for treating the colon cancer is expected to be developed on the basis of the compound.

Microwave-assisted click chemistry synthesis of 1,2,3-triazoles from aryldiazonium silica sulfates in water

A microwave-assisted click chemistry synthesis of 1,4-disubstituted 1,2,3-triazoles is studied by in situ generation of aryl azides via the reaction of aryldiazonium silica sulfates and sodium azide, followed by coupling with a terminal alkyne in the presence of copper catalyst. These reactions are carried out in water under mild and heterogeneous conditions without using any additional ligands.