1673-08-1

Basic information

• Product Name: cyclohexyl palmitate
• Synonyms: cyclohexyl palmitate;Hexadecanoic acid cyclohexyl ester;Palmitic acid cyclohexyl ester
• CAS NO: 1673-08-1
• Molecular Formula: C₂₂H₄₂O₂
• Molecular Weight: 338.56768
• EINECS: 216-810-4
• Mol File: 1673-08-1.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 393.1°Cat760mmHg
• Flash Point: 172.6°C
• Appearance: /
• Density: 0.9g/cm³
• Vapor Pressure: 2.18E-06mmHg at 25°C
• Refractive Index: 1.465
• CAS DataBase Reference: cyclohexyl palmitate(CAS DataBase Reference)
• NIST Chemistry Reference: cyclohexyl palmitate(1673-08-1)
• EPA Substance Registry System: cyclohexyl palmitate(1673-08-1)

Safety Data

• Hazardous Substances Data: 1673-08-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C22H42O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-17-20-22(23)24-21-18-15-14-16-19-21/h21H,2-20H2,1H3

Upstream product

• 108-93-0 cyclohexanol 
• 112-67-4 n-hexadecanoyl chloride 
• 57-10-3 1-hexadecylcarboxylic acid 

Relevant articles and documents

Biomass derived β-cyclodextrin-SO3H as a solid acid catalyst for esterification of carboxylic acids with alcohols

A novel β-cyclodextrin-SO3H carbon based solid acid catalyst was prepared in a convenient and ecofriendly manner and was characterized using FTIR, PXRD, EDAX and NH3TPD to illustrate that the carbon material has been functionalized with -SO3H, -COOH and -OH groups. The catalyst was studied for esterification of various carboxylic acids and alcohols under solvent free conditions and showed excellent catalytic performance and gave good yields of esters in the range 78-99% at 70°C. No solvent was used either for catalyst preparation nor for esterification reaction. The catalyst can be easily recovered by simple filtration and reused for subsequent three runs without any significant impact on yields of products. The main advantage of this methodology is easy and ecofriendly catalyst preparation, easy catalyst separation, practical simplicity, safe reaction conditions, recyclable catalyst and high product yields.

Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase

N-Acylethanolamines, including N-palmitoyl-ethanolamine (PEA), are hydrolyzed to the corresponding fatty acids and ethanolamine by fatty acid amide hydrolase (FAAH). Recently, N-acylethanolamine-hydrolyzing acid amidase (NAAA) was identified as being able to specifically hydrolyze PEA. In order to find selective and effective inhibitors of this enzyme, we synthesized and screened several amides, retroamides, esters, retroesters and carbamates of palmitic acid (1-21) and esters with C15 and C17 alkyl chains (22-27). Cyclopentylhexadecanoate (13) exhibited the highest inhibitory activity on NAAA (IC50 = 10.0 μM), without inhibiting FAAH up to 50 μM. Compound 13 may become a useful template to design new NAAA inhibitors.