1674386-82-3 Usage
Description
Lipoamido-PEG2-alcohol is a versatile linker that features a lipoamide moiety and a reactive alcohol group. This alcohol group allows for further derivatization of the compound, enhancing its potential applications. The hydrophilic PEG spacer significantly improves the compound's water solubility in aqueous media, making it suitable for various uses in different industries.
Uses
Used in Pharmaceutical Industry:
Lipoamido-PEG2-alcohol is used as a molecular linker for enhancing the solubility and stability of therapeutic agents. Its ability to derivatize and improve water solubility makes it an ideal candidate for the development of novel drug delivery systems and formulations.
Used in Biochemical Research:
In the field of biochemical research, Lipoamido-PEG2-alcohol serves as a valuable tool for the conjugation of biologically active molecules, such as peptides, proteins, and other macromolecules. This allows for the creation of new bioconjugates with improved properties and potential applications in research and therapeutics.
Used in Diagnostics:
Lipoamido-PEG2-alcohol is used as a component in the development of diagnostic tools, such as imaging agents and biosensors. Its hydrophilic nature and ability to derivatize make it suitable for creating contrast agents or probes that can be used in various diagnostic techniques.
Used in Material Science:
In material science, Lipoamido-PEG2-alcohol can be utilized as a building block for the synthesis of novel materials with specific properties. Its hydrophilic PEG spacer and reactive alcohol group enable the creation of materials with tailored characteristics, such as improved biocompatibility, enhanced water solubility, or specific binding affinities.
Overall, Lipoamido-PEG2-alcohol is a multifaceted compound with a wide range of potential applications across various industries, thanks to its unique structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 1674386-82-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,7,4,3,8 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1674386-82:
(9*1)+(8*6)+(7*7)+(6*4)+(5*3)+(4*8)+(3*6)+(2*8)+(1*2)=213
213 % 10 = 3
So 1674386-82-3 is a valid CAS Registry Number.
1674386-82-3Relevant articles and documents
Lipase-catalyzed amidation of carboxylic acid and amines
Manova, Daniela,Gallier, Florian,Tak-Tak, Lotfi,Yotava, Lyubov,Lubin-Germain, Nadège
, p. 2086 - 2090 (2018)
The amidation reaction is of a very particular interest, especially in the pharmaceutical industry and always requires the activation of the acid with a large excess of reactants. Therefore, a large amount of waste is generated. In order to reduce the environmental impact of such reaction, we have developed enzymatic amidation conditions which are compatible with a wide range of amines and acids, in particular with the biologically relevant lipoic acid. Water is the only by-product generated during this reaction thus a very high atom economy is obtained. In addition, we have shown that the lipase can be recovered and reused several times without a significant loss of activity.
