16744-89-1Relevant articles and documents
Cyclopentanone ring expansion leading to functionalized δ-lactams: Short synthesis of simple sedum alkaloids
Maio, William A.,Sinishtaj, Sandra,Posner, Gary H.
, p. 2673 - 2676 (2007)
Equation Presented Monosubstituted epoxides react with (cyclopentenyloxy) trimethylsilane to afford, after subsequent oxidative fragmentation, a pair of diastereomeric 8-membered iodolactones. When these lactones are separately treated with sodium azide,
AZEPANE DERIVATIVES AND METHODS OF TREATING HEPATITIS B INFECTIONS
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Paragraph 0704, (2015/09/22)
Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
A concise approach towards the synthesis of WS75624 a and WS75624 B via the cross-metathesis of vinyl-functionalized thiazoles
Dash, Jyotirmayee,Melillo, Bruno,Arseniyadis, Stellios,Cossy, Janine
experimental part, p. 2246 - 2249 (2011/05/05)
Synthetic approach towards precursors of WS75624 A and WS75624 B, two potent endothelin converting enzyme (ECE) inhibitors and potential antihypertensive agents, is reported featuring a key cross-metathesis between a vinyl-functionalized thiazole and a terminal olefin. As the two natural products only differ by the nature of their hydroxyalkyl side-chain, our convergent strategy enable the synthesis of key intermediates of both molecules in a limited amount of steps.