167566-34-9

Basic information

• Product Name: 1-benzyl-3-(trifluoromethyl)piperazine
• Synonyms: 1-benzyl-3-(trifluoromethyl)piperazine
• CAS NO: 167566-34-9
• Molecular Formula: C12H15F3N2
• Molecular Weight: 244.2561096
• Mol File: 167566-34-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 275.3±35.0 °C(Predicted)
• Appearance: /
• Density: 1.191±0.06 g/cm3(Predicted)
• PKA: 6.74±0.40(Predicted)
• CAS DataBase Reference: 1-benzyl-3-(trifluoromethyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-3-(trifluoromethyl)piperazine(167566-34-9)
• EPA Substance Registry System: 1-benzyl-3-(trifluoromethyl)piperazine(167566-34-9)

Safety Data

• Hazardous Substances Data: 167566-34-9(Hazardous Substances Data)

Usage

Chemical structure

Piperazine derivative with a benzyl group and a trifluoromethyl group attached to the piperazine ring

Pharmacological properties

a. Antidepressant potential
b. Anxiolytic potential

Application

a. As a precursor in organic synthesis
b. Potential use in the development of new drugs

Safety precautions

Handle with caution due to potential hazards if not used properly

Upstream product

• 91944-47-7 3,3,3-Trifluoropyruvaldehyde 
• 4152-09-4 N-benzylethylenediamine 
• 431-67-4 1,1-dibromo-3,3,3-trifluoroacetone 

Downstream Products

• 131922-05-9 (+/-)-2-(trifluoromethyl)piperazine 

Relevant articles and documents

BIS-HETEROARYL DERIVATIVES AS MODULATORS OF PROTEIN AGGREGATION

The present invention relates to certain bis-heteroaryl compounds, pharmaceutical compositions containing them, and methods of using them, including methods for preventing, reversing, slowing, or inhibiting protein aggregation, and methods of treating diseases that are associated with protein aggregation, including neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease, Lewy body disease, Parkinson's disease with dementia, fronto- temporal dementia, Huntington's Disease, amyotrophic lateral sclerosis, and multiple system atrophy, and cancer including melanoma.

NOVEL BENZOFURAN DERIVATIVES, WHICH CAN BE USED IN PROPHYLAXIS OR TREATMENT OF 5-HT6 RECEPTOR-RELATED DISORDER

The present invention relates to compounds of formula (I): wherein P, R3, W1, and W2 are as described herein, to pharmaceutical compositions comprising the compounds, to processes for their preparation, as well as to the use of the compounds for the preparation of a medicament against 5-HT6 receptor-related disorders.