1678-53-1

Basic information

• Product Name: 3-Methyl-4-nitropyridine
• Synonyms: 3-METHYL-4-NITROPYRIDINE;4-NITRO-3-PICOLINE;4-NITRO-3-PICOLINE HCL;IFLAB-BB F1371-0142;4-Nitro-3-picoline hydrochloride;4-Nitro-3-methylpyridine
• CAS NO: 1678-53-1
• Molecular Formula: C₆H₆N₂O₂
• Molecular Weight: 138.12
• EINECS: -0
• Product Categories: Pyridine;Pyridines, Pyrimidines, Purines and Pteredines;Pyridines
• Mol File: 1678-53-1.mol
• Article Data: 2

Chemical Properties

• Melting Point: 28-29 °C(Solv: ligroine (8032-32-4))
• Boiling Point: 244.2 °C at 760 mmHg
• Flash Point: 101.5 °C
• Appearance: Light yellow powder
• Density: 1.246 g/cm³
• Vapor Pressure: 0.0481mmHg at 25°C
• Refractive Index: 1.558
• PKA: 1.61±0.18(Predicted)
• CAS DataBase Reference: 3-Methyl-4-nitropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-4-nitropyridine(1678-53-1)
• EPA Substance Registry System: 3-Methyl-4-nitropyridine(1678-53-1)

Safety Data

• Hazardous Substances Data: 1678-53-1(Hazardous Substances Data)

Usage

Chemical Properties

Light yellow powder

InChI:InChI=1/C6H6N2O2/c1-5-4-7-3-2-6(5)8(9)10/h2-4H,1H3

Upstream product

• 1990-90-5 4-amino-3-methylpyridine 
• 1074-98-2 3-methyl-4-nitropyridine N-oxide 
• 1003-73-2 3-picoline-N-oxide 

Downstream Products

• 1990-90-5 4-amino-3-methylpyridine 
• 100367-58-6 4-Nitro-nicotinsaeure 
• 856966-91-1 3-Methyl-5-nitro-1H-pyridin-4-one 
• 271-34-1 5-azaindole 
• 109113-39-5 1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine 
• 148760-75-2 tert-butyl 1H-pyrrolo[3,2-c]pyridine-1-carboxylate 
• 109113-44-2 1-Benzenesulfonyl-2-formyl-1H-pyrrolo<3,2-c>pyridine 
• 109113-41-9 1-benzenesulphonyl-2-acetyl-1H-pyrrolo[3,2-c]pyridine 
• 109113-45-3 1-Benzenesulfonyl-2-hydroxycarbonyl-1H-pyrrolo<3,2-c>pyridine 
• 125335-95-7 2-(1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine)-4-(3-diethylaminocarbonyl-2-methoxypyridyl)ketone 
• 148729-71-9 2-(1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine)-4-(3-diethylaminocarbonyl-2-methoxypyridyl)methanol 
• 148729-73-1 2-(1-Benzenesulfonyl-1H-pyrrolo<3,2-c>pyridine)-4-(3-diethylaminocarbonyl-2-methoxypyridyl)-1,1-ethanol 
• 101870-39-7 N-(3-methyl-[4]pyridyl)-formamide 
• 1074-98-2 3-methyl-4-nitropyridine N-oxide 

Relevant articles and documents

Metallation in connection with cross-coupling reactions. Coupling of hindered aryls for the synthesis of 4-phenylpyridines as part of Streptonigrin and Lavendamycin analogues

The synthesis of the C-D ring system of Streptonigrin and Lavendamycln alkaloid analogues by cross-coupling under Suzuki's conditions has been studied. Steric hindrance is the main problem. It has been solved either by using strong bases or working in a sealed tube under pressure.