167947-08-2Relevant articles and documents
Anesthetic activity of novel water-soluble 2β-morpholinyl steroids and their modulatory effects at GABA(A) receptors
Anderson, Alison,Boyd, Andrew C.,Byford, Alan,Campbell, Alexander C.,Gemmell, David K.,Hamilton, Niall M.,Hill, David R.,Hill-Venning, Claire,Lambert, Jeremy J.,Maidment, Maurice S.,May, Valerie,Marshall, Richard J.,Peters, John A.,Rees, David C.,Stevenson, Donald,Sundaram, Hardy
, p. 1668 - 1681 (2007/10/03)
(3α,5α)-3-Hydroxypregnan-20-ones and (3α,5α)-3-hydroxypregnane- 11,20-diones bearing a 2β-morpholinyl substituent were synthesized, and the utility of these steroids as anesthetic agents was evaluated through determination of their potency and duration of