168038-14-0 Usage
Description
(R)-2-Methyl-morpholine is a chiral organic compound belonging to the morpholine family. It is characterized by its asymmetric carbon atom, which gives it a specific stereochemistry. (R)-2-Methyl-morpholine is known for its unique properties and reactivity, making it a valuable building block in the synthesis of various pharmaceuticals and organic compounds.
Uses
Used in Pharmaceutical Industry:
(R)-2-Methyl-morpholine is used as a reactant in the preparation of naphthyridine as a hedgehog protein modulator. It plays a crucial role in the synthesis process, where it is derived from chloronicotinonitrile via aryl amination of naphthyridine halide. This application is significant in the development of drugs targeting the hedgehog signaling pathway, which is implicated in various diseases, including cancer and congenital disorders.
Additionally, due to its unique properties and reactivity, (R)-2-Methyl-morpholine can be employed as a building block or intermediate in the synthesis of other pharmaceuticals and organic compounds. Its chiral nature and ability to form stable complexes with various functional groups make it a versatile component in the design and development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 168038-14-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,8,0,3 and 8 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 168038-14:
(8*1)+(7*6)+(6*8)+(5*0)+(4*3)+(3*8)+(2*1)+(1*4)=140
140 % 10 = 0
So 168038-14-0 is a valid CAS Registry Number.
168038-14-0Relevant articles and documents
PYRAZOLO[3,4-D]PYRIMIDIN DERIVATIVE AND ITS USE FOR THE TREATMENT OF LEISHMANIASIS
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Page/Page column 37, (2016/08/17)
The compound 3,3,3-trifluoro-N-((1,4-trans)-4-((3-((S)-2-methylmorpholino)-1H- pyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamidehaving the Formula (I) or a salt thereof, its opposite enantiomer, compositions comprising the compound and its use in the treatment or prevention of leishmaniasis, particularly visceral leishmaniasis.
CHROMENONE DERIVATIVES
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, (2012/10/23)
The invention concerns chromenone compounds of Formula I; or pharmaceutically-acceptable salts thereof, wherein each of R1, R2, R3, R4, R5, n and R6 has any of the meanings defined hereinbe
COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS
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Page/Page column 116-117, (2009/09/05)
The invention provides a novel class of 2,7-naphthyridin derivatives; pharmaceutical compositions comprising such compounds and methods of using such compounds to treat o prevent diseases or disorders associated with abnormal or deregulated kinase activit
