16807-48-0

Basic information

• Product Name: DEHYDROACETIC ACID
• Synonyms: 3-Acetyl-2-hydroxy-6-methyl-4H-pyran-4-one;Dehydroacetic acid [iso]
• CAS NO: 16807-48-0
• Molecular Formula: C₈H₈O₄
• Molecular Weight: 168.15
• EINECS: 208-293-9
• Mol File: 16807-48-0.mol
• Article Data: 1

Chemical Properties

• Melting Point: 109-112℃
• Boiling Point: 332.6°C at 760 mmHg
• Flash Point: 150.5°C
• Appearance: /
• Density: 1.264g/cm³
• Vapor Pressure: 0.000144mmHg at 25°C
• Refractive Index: 1.489
• PKA: 4.50±1.00(Predicted)
• CAS DataBase Reference: DEHYDROACETIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: DEHYDROACETIC ACID(16807-48-0)
• EPA Substance Registry System: DEHYDROACETIC ACID(16807-48-0)

Safety Data

• Hazard Codes: Xn:Harmful
• Statements: R22:
• Hazardous Substances Data: 16807-48-0(Hazardous Substances Data)

Usage

General Description

Dehydroacetic acid is a synthetic compound used primarily as a preservative in cosmetics, pharmaceuticals, and food products. It is known for its broad antimicrobial spectrum and ability to inhibit the growth of various microorganisms, including bacteria and fungi. Dehydroacetic acid works by disrupting the cellular function of microorganisms, preventing them from reproducing and causing spoilage or contamination in products. It is considered safe for use in regulated concentrations and is approved for use in various countries around the world. However, some individuals may have sensitivities to dehydroacetic acid, so it is important to use products containing this chemical with caution.

InChI:InChI=1/C8H8O4/c1-4-3-6(10)7(5(2)9)8(11)12-4/h3,7H,1-2H3

Upstream product

• 141-97-9 ethyl acetoacetate 

Downstream Products

• 615-15-6 2-Methyl-1H-benzimidazole 
• 615-16-7 1,3-dihydro-2H-benzimidazol-2-one 
• 111008-23-2 4-(2-oxopropylidene)-1,2,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one 
• 127782-81-4 [4-Methyl-1,3-dihydro-benzo[b][1,4]diazepin-(2E)-ylidene]-acetic acid methyl ester 
• 127782-83-6 [4-Methyl-1,3-dihydro-benzo[b][1,4]diazepin-(2E)-ylidene]-acetic acid propyl ester 
• 127782-82-5 [4-Methyl-1,3-dihydro-benzo[b][1,4]diazepin-(2E)-ylidene]-acetic acid ethyl ester 
• 127782-85-8 4-[2-[(E)-2-Amino-phenylimino]-prop-(E)-ylidene]-1,3,4,5-tetrahydro-benzo[b][1,4]diazepin-2-one 
• 54107-17-4 4-hydroxy-6-methyl-3-[(1E)-1-(2-phenylhydrazinylidene)ethyl]-2H-pyran-2-one 
• 64804-27-9 para-N,N'-phenylene-diylbis[3-(1-aminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione] 
• 1353892-13-3 C₂₂H₁₈⁽²⁾H₂N₂O₆ 
• 865375-39-9 ortho-N,N'-phenylene-diylbis[3-(1-aminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione] 
• 64804-28-0 meta-N,N'-phenylene-diylbis[3-(1-aminoethyl)-6-methyl-2H-pyran-2,4(3H)-dione] 
• 137934-94-2 3-hydroxy-5-methyl-4-<3'-methyl-1'-phenylpyrazol-5'-yl>-1-phenylpyrazole 
• 54162-06-0 5-anilino-3,6-dimethyl-4-oxo-1-phenylpyrazolo<4,3-c>pyridine 

Related news

Ruthenium (II) complexes containing DEHYDROACETIC ACID (cas 16807-48-0) and its imine derivative ligands. Synthesis, characterization and cancer cell growth anti-proliferation activity (GI50) study07/21/2019

Two dehydroacetic acid (DHA, L1H) related imine ligands, L2H and L3H were obtained in moderate yields by reacting DHA with 2,4,6-trimethylaniline and phenylhydrazine, respectively. Refluxing [Ru (η6-p-cymene)Cl2]2 with two equivalents of L1Na, L2H and L3H in methanol generated ruthenium compoun...detailed

Relevant articles and documents

2,7-Dimethyl-4H-pyrano-2H-pyran-4,5-dione, a Novel Product in the Base-catalysed Self-condensation of Ethyl Acetoacetate : Carbon-13 NMR Spectral Studies

Self-condensation of ethyl acetoacetate (EAA) in the presence of a small amount of sodium bicarbonate affords, in addition to the earlier reported dehydroacetic acid (II) (45 percent), a new fused γ-pyrono-pyrone derivative in 40 percent yield, the structure of which has been shown to be 2,7-dimethyl-4H-pyrano-2H-pyran-4,5-dione (III) mainly based on PMR and 13C NMR spectral results and supported by UV, IR and mass spectral data.Compound (II) upon refluxing with EAA in water containing pyridine gives III while EAA under similar condition neither affords II nor III and remains mostly unchanged, supporting the postulated mechanism of formation of III via II. 13C NMR spectral data of II have also been discussed.