1681-37-4 Usage
Description
4-Amino-3-nitropyridine is a chemical compound characterized as a yellow crystalline powder. It is a derivative of pyridine, a heterocyclic organic compound, with an amino group at the 4th position and a nitro group at the 3rd position. 4-Amino-3-nitropyridine is known for its unique chemical properties and is utilized in various applications, particularly in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
4-Amino-3-nitropyridine is used as a pharmaceutical intermediate for the synthesis of various drugs and medications. Its unique chemical structure allows it to serve as a building block in the development of new pharmaceutical compounds, contributing to the advancement of medical treatments.
As a Chemical Intermediate:
4-Amino-3-nitropyridine is used as a chemical intermediate in the synthesis of various organic compounds. Its reactivity and functional groups make it a valuable component in the production of a wide range of chemicals, including those used in the pharmaceutical, agrochemical, and material science industries.
In Research and Development:
4-Amino-3-nitropyridine is also utilized in research and development settings, where it is employed to study the properties and behavior of various chemical reactions. Its use in this context aids in the discovery and development of new compounds and materials with potential applications in various fields.
Check Digit Verification of cas no
The CAS Registry Mumber 1681-37-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,6,8 and 1 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1681-37:
(6*1)+(5*6)+(4*8)+(3*1)+(2*3)+(1*7)=84
84 % 10 = 4
So 1681-37-4 is a valid CAS Registry Number.
InChI:InChI=1/C5H5N3O2/c6-4-1-2-7-3-5(4)8(9)10/h1-3H,(H2,6,7)/p+1
1681-37-4Relevant articles and documents
The oxidative amination of 3-nitropyridines
Bakke, Jan M,Svensen, Harald
, p. 4393 - 4395 (2007/10/03)
3-Nitropyridine was reacted with ammonia or alkylamines and KMnO4 under several different conditions. Substitutions in the para position to the nitro group were obtained with high regioselectivity: with ammonia, 2-amino-5-nitropyridine (66%), w
Regioselectivity of the Amination of Some 3-Nitropyridines by Liquid Ammonia / Potassium Permanganate
Wozniak, Marian,Baranski, Andrzej,Szpakiewicz, Barbara
, p. 875 - 878 (2007/10/02)
3-Nitropyridine and some of its derivatives are aminated in a liquid ammonia solution of potassium permanganate to the corresponding 2- and (or) 4- and (or) 6-amino compounds.Quantumchemical calculations for a few 3-nitropyridines suggest that the experimentally observed regioselectivity of the amination is controlled by Coulombic interaction. --- Key Words: Amination / Nitropyridines / Reactivity indices / Calculations, MNDO
