168123-76-0

Basic information

• Product Name: 5,7-dichloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione
• Synonyms: 5,7-dichloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione;5,7-Dichloro-1,4-dihydro-pyrido[3,4-b]pyrazine-2,3-dione
• CAS NO: 168123-76-0
• Molecular Formula: C7H3Cl2N3O2
• Molecular Weight: 232.02362
• Mol File: 168123-76-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,7-dichloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-dichloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione(168123-76-0)
• EPA Substance Registry System: 5,7-dichloropyrido[3,4-b]pyrazine-2,3(1H,4H)-dione(168123-76-0)

Safety Data

• Hazardous Substances Data: 168123-76-0(Hazardous Substances Data)

Upstream product

• 101079-63-4 3,4-diamino-2,6-dichloropyridine 

Relevant articles and documents

8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/NMDA receptor

Disclosed is a method of treating or preventing neuronal loss associated with stroke, ischemia, CNS trauma or hypoglycemia. The method comprises administering to an animal a compound of the formula: STR1 or a pharmaceutically acceptable salt thereof; wherein n is zero or 1; R 4, R 5, R 6 are independently hydrogen, nitro, amino, halo, haloalkyl, cyano, alkyl, cycloalkyl, alkenyl, alkynyl, azido, acylamino, alkylsulfonyl, aryl, substituted aryl, heteroaryl, alkoxy, trialkylsilyl-substituted alkoxy, aryloxy, substituted aryloxy, heteroaryloxy, a heterocyclic group, a heterocyclicoxy group, aralkoxy, or haloalkoxy; and R c and R d are defined in the specification. These compounds have high binding to the glycine site of the NMDA receptor.