16840-37-2Relevant articles and documents
Shoppee,Newman
, p. 981 (1968)
Stefanovic et al.
, p. 1895,1899,1900 (1970)
CHEMISTRY OF SINGLET OXYGEN. 47. 9,10-DICYANOANTHRACENE-SENSITIZED PHOTOOXYGENATION OF ALKYL-SUBSTITUTED OLEFINS.
Araki,Dobrowolski,Goyne,Hanson,Zhi Qui Jiang,Lee,Foote
, p. 4570 - 4575 (1984)
9,10-Dicyanoanthracene (DCA) sensitizes the photooxygenation of 1-methylcyclohexene, 1,2-dimethylcyclohexene, and cholesterol in acetonitrile and benzene. For all three olefins, the products are the same as those formed by reaction with singlet oxygen. Th
Cholesterol hydroperoxides generate singlet molecular oxygen [O 2(1Δg)]: Near-IR emission, 18O-labeled hydroperoxides, and mass spectrometry
Uemi, Miriam,Ronsein, Graziella E.,Prado, Fernanda M.,Motta, Flavia D.,Miyamoto, Sayuri,Medeiros, Marisa H. G.,Di Mascio, Paolo
experimental part, p. 887 - 895 (2012/04/11)
In mammalian membranes, cholesterol is concentrated in lipid rafts. The generation of cholesterol hydroperoxides (ChOOHs) and their decomposition products induces various types of cell damage. The decomposition of some organic hydroperoxides into peroxyl
Kinetic studies of cholesterol oxidation as inhibited by stearylamine during heating
Chien, John-Tung,Huang, Dong-Yong,Chen, Bing-Huei
, p. 7132 - 7138 (2007/10/03)
The formation of cholesterol oxidation products (COPs) during heating in the presence of stearylamine at 140°C was analyzed by high-performance liquid chromatography (HPLC) and kinetically studied by use of nonlinear regression models. Results indicated that the COPs concentration increased with increasing heating time, and stearylamine was shown to reduce both oxidation and degradation rates of cholesterol. Without stearylamine, the highest rate constant (per hour) was observed for epoxidation (545.4), followed by free radical chain reaction (251.0), reduction (147.3), dehydration (95.8), triol dehydrogenation (4.7), degradation (0.34), triol formation (0.31), and dehydrogenation (0.13). With stearylamine, the epoxidation and free radical chain reaction rates could be reduced by about 800- and 3.4-fold, respectively, and triol formation during oxidation could be completely inhibited. In addition, the reactions for reduction, dehydration, degradation, and dehydrogenation could proceed slower in the presence of stearylamine. The kinetic model developed in this study can be used to predict the inhibition of COPs formation by stearylamine during heating of cholesterol.