16860-32-5Relevant articles and documents
Electrochemical Oxidation of 1-Phenylpyrazolidin-3-ones. Part 3. Reaction Mechanism
Bellamy, Anthony J.,Innes, David I.,Hillson, Peter J.
, p. 179 - 182 (2007/10/02)
A cyclic voltammetric study of 1-phenylpyrazolidin-3-one and some typical substituted analogues has shown that the chemical step following the initial electron transfer involves deprotonation of the cation-radical at position 2 (NH).In the abscence of added base and at substrate concentration >2mM, the substrate itself deprotonates the cation-radical.In the presence of basic chloride ions oxidation occurs via the conjugate base of 1-phenylpyrazolidin-3-one.The lifetime of the cation-radical is relatively insensitive to the nature of the substituents at C(4) and C(5), but is increased markedly by substitution at N(2).