168828-71-5

Basic information

• Product Name: benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate
• Synonyms: benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate;Benzyl N-[3-fluoro-4-(thiomorpholin-4-yl)phenyl]carbamate;benzyl (3-fluoro-4-thiomorpholinophenyl)carbamate(WXC06629)
• CAS NO: 168828-71-5
• Molecular Formula: C₁₈H₁₉FN₂O₂S
• Molecular Weight: 346.43
• Mol File: 168828-71-5.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate(168828-71-5)
• EPA Substance Registry System: benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate(168828-71-5)

Safety Data

• Hazardous Substances Data: 168828-71-5(Hazardous Substances Data)

Usage

General Description

Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate is a chemical compound with the molecular formula C17H19FN2O2S. It is an organic compound that belongs to the class of carbamates. benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate is used in various fields such as pharmaceuticals, agrochemicals, and materials science. Benzyl(3-fluoro-4-thiomorpholinophenyl)carbamate has potential biological and pharmacological activities, and it is commonly used as an intermediate in the synthesis of various active pharmaceutical ingredients. Its unique chemical structure and properties make it an important and versatile compound in the field of organic chemistry.

Upstream product

• 501-53-1 benzyl chloroformate 
• 237432-11-0 (3-fluoro-4-thiomorpholin-4-ylphenyl)amine 
• 369-34-6 3,4-difluoronitrobenzene 
• 168828-70-4 (4-(2-fluoro-4-nitrophenyl)thiomorpholine) 
• 75-09-2 dichloromethane 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 168828-72-6 (R)-<3-<3-fluoro-4-(4-thiomorpholinyl)phenyl>-2-oxo-5-oxazolidinyl>methanol 
• 343869-84-1 (S)-3-[3-fluoro-4-(4-thiomorpholinyl)phenyl]-5-hydroxyethyl-oxazolidine-2-one 
• 216869-36-2 (5S)-5-(aminomethyl)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-1,3-oxazolidin-2-one 
• 168828-58-8 sutezolid 
• 168828-74-8 (R)-<3-<3-fluoro-4-(4-thiomorpholinyl)phenyl>-2-oxo-5-oxazolidinyl>methyl azide 
• 168828-60-2 N-[[(5S)-3-[3-fluoro-4-(1-oxido-4-thiomorpholinyl)phenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide 
• 168828-73-7 Toluene-4-sulfonic acid (R)-3-(3-fluoro-4-thiomorpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl ester 
• 1215197-17-3 (5S)-5-{[((E)-4-chlorobenzylidene)amino]methyl}-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-1,3-oxazolidin-2-one 

Relevant articles and documents

Spectroscopic identification of intermediates and final products of the chiral pool synthesis of sutezolid

Sutezolid is a new oxazolidinone derivative currently in clinical trials to determine its safety and efficacy towards highly drug-resistant tuberculosis. The aim of the study was the spectroscopic identification of selected key intermediate products of th

Syntheses and antibacterial activity studies of new oxazolidinones from nitroso Diels-Alder chemistry

A series of novel oxazolidinone antibiotics having [2.2.1] and [2.2.2] bicyclic oxazine moieties at the C-5 side chain of the A-ring was synthesized by nitroso Diels-Alder reactions, from three linezolid analogs containing morpholine, piperazine and thiomorpholine, respectively, as the C-ring components. Subsequent N-O bond cleavage generated oxazolidinones with 4-amino cyclo-2-en-1-ol substituents. The in vitro antibacterial activities of these oxazolidinone analogs were evaluated.

Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity.

During the course of our investigations in the oxazolidinone antibacterial agent area, we have identified a subclass with especially potent in vitro activity against mycobacteria. The salient structural feature of these oxazolidinone analogues, 6 (U-10048