168893-24-1

Basic information

• Product Name: 5-Amino-1-[methylamino(thiocarbonyl)]-3-phenyl-1H-1,2,4-triazole
• CAS NO: 168893-24-1
• Molecular Weight: 233.297
• Mol File: 168893-24-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-Amino-1-[methylamino(thiocarbonyl)]-3-phenyl-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Amino-1-[methylamino(thiocarbonyl)]-3-phenyl-1H-1,2,4-triazole(168893-24-1)
• EPA Substance Registry System: 5-Amino-1-[methylamino(thiocarbonyl)]-3-phenyl-1H-1,2,4-triazole(168893-24-1)

Safety Data

• Hazardous Substances Data: 168893-24-1(Hazardous Substances Data)

Upstream product

• 3679-92-3 N-(benzamido)-guanidine 
• 613-94-5 benzoic acid hydrazide 
• 4922-98-9 3-phenyl-1H-1,2,4-triazol-5-amine 
• 556-61-6 methyl thioisocyanate 

Relevant articles and documents

Triazole derivative and pharmaceutical use thereof

An agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, an agent for the prophylaxis and treatment of allergic diseases, an agent for the prophylaxis and treatment of eosinophil-related diseases and an eosinophilia inhibitor, comprising, as an active ingredient, a series of triazole derivatives of the following formula (I) STR1 or the following formula (III) STR2 wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof. A novel monocyclic or bicyclic triazole derivative. The agent for the prophylaxis and treatment of immune-related diseases, in particular, immunosuppressant, the agent for the prophylaxis and treatment of allergic diseases, the agent for the prophylaxis and treatment of eosinophil-related diseases, the eosinophilia inhibitor and the novel triazole derivative of the present invention all, have superior eosinophilia-inhibitory action and lymphocyte activation-inhibitory action. They are low toxic and persistent in action. They are particularly effective in the treatment of accumulation and activation of eosinophil and lymphocytes, inflammatory respiratory tract diseases, eosinophil-related diseases such as eosinophilia, and immune-related diseases.