168900-02-5

Basic information

• Product Name: 3-(2,4-dichlorophenyl)-6-fluoro-quinazoline-2,4(1H,3H)-dione
• Synonyms: 3-(2,4-dichlorophenyl)-6-fluoro-quinazoline-2,4(1H,3H)-dione
• CAS NO: 168900-02-5
• Molecular Formula: C14H7 Cl2 F N2 O2
• Molecular Weight: 325.12
• EINECS: 412-190-6
• Mol File: 168900-02-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Density: 1.558g/cm³
• Refractive Index: 1.64
• PKA: 10.56±0.20(Predicted)
• CAS DataBase Reference: 3-(2,4-dichlorophenyl)-6-fluoro-quinazoline-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2,4-dichlorophenyl)-6-fluoro-quinazoline-2,4(1H,3H)-dione(168900-02-5)
• EPA Substance Registry System: 3-(2,4-dichlorophenyl)-6-fluoro-quinazoline-2,4(1H,3H)-dione(168900-02-5)

Safety Data

• Hazard Codes: N
• Statements: 50/53
• Safety Statements: 60-61
• Hazardous Substances Data: 168900-02-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H7Cl2FN2O2/c15-7-1-4-12(10(16)5-7)19-13(20)9-6-8(17)2-3-11(9)18-14(19)21/h1-6H,(H,18,21)

Relevant articles and documents

Process for the preparation of substituted 3-arylquinazoline-2,4-diones

The invention relates to a process for the preparation of substituted 3-arylquinazoline-2,4-diones of the formula (I) STR1 in which R1, R2, R3 and R4 are as defined in claim 1 and Ar is STR2 where R5 to R9 are as defined in claim 1, by reacting a compound of the formula (II) STR3 with a compound Z in the presence of a catalyst, a ligand and a solvent, where Z is a) an anthranilic acid derivative of the formula (III) STR4 or b) an alcohol R10 --OH and where, in case b), the resulting carbamate is then reacted with an anthranilic acid derivative of the formula III.