168915-00-2Relevant articles and documents
Synthesis of 4,6-disubstituted pyrimidines via Suzuki and Kumada coupling reaction of 4,6-dichloropyrimidine
Qing, Feng-ling,Wang, Ruowen,Li, Benhan,Zheng, Xing,Meng, Wei-Dong
, p. 21 - 24 (2003)
A series of 4,6-disubstituted pyrimidines were synthesized via Suzuki and Kumada coupling reaction of 4,6-dichloropyrimidine.
Design, synthesis, and evaluation of novel biarylpyrimidines: A new class of ligand for unusual nucleic acid structures
Wheelhouse, Richard T.,Jennings, Sharon A.,Phillips, Victoria A.,Pletsas, Dimitrios,Murphy, Peter M.,Garbett, Nichola C.,Chaires, Jonathan B.,Jenkins, Terence C.
, p. 5187 - 5198 (2008/04/18)
Biarylpyrimidines are characterized as selective ligands for higher-order nucleic acid structures. A concise and efficient synthesis has been devised incorporating Suzuki biaryl cross-coupling of dihalopyrimidines. Two ligand series are described based on