16897-97-5

Basic information

• Product Name: 2-(2-BROMOPHENYL)ACETOPHENONE
• Synonyms: 2-(2-BROMOPHENYL)-1-PHENYLETHAN-1-ONE;2-(2-BROMOPHENYL)ACETOPHENONE;2-(2-bromophenyl)-1-phenylethanone
• CAS NO: 16897-97-5
• Molecular Formula: C₁₄H₁₁BrO
• Molecular Weight: 275.14
• Mol File: 16897-97-5.mol
• Article Data: 23

Chemical Properties

• Melting Point: 66-67 °C
• Boiling Point: 371.7°C at 760 mmHg
• Flash Point: 76.4°C
• Appearance: /
• Density: 1.39g/cm³
• Vapor Pressure: 1.01E-05mmHg at 25°C
• Refractive Index: 1.608
• CAS DataBase Reference: 2-(2-BROMOPHENYL)ACETOPHENONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-BROMOPHENYL)ACETOPHENONE(16897-97-5)
• EPA Substance Registry System: 2-(2-BROMOPHENYL)ACETOPHENONE(16897-97-5)

Safety Data

• Hazardous Substances Data: 16897-97-5(Hazardous Substances Data)

Usage

Appearance

White solid

Melting point

75-77°C

Usage

Organic synthesis, pharmaceutical research

Common applications

Intermediate in the production of pharmaceutical drugs, reagent in the synthesis of complex organic compounds

Importance

Versatile chemical, key building block for development of new drug candidates and biologically active molecules in pharmaceutical and chemical industries.

InChI:InChI=1/C14H11BrO/c15-13-9-5-4-8-12(13)10-14(16)11-6-2-1-3-7-11/h1-9H,10H2

Upstream product

• 98-88-4 benzoyl chloride 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 18698-97-0 ortho-bromophenylacetic acid 
• 71-43-2 benzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 98-86-2 acetophenone 
• 55116-09-1 2-bromophenylacetyl chloride 
• 21375-88-2 1-bromo-2-(phenylethenyl)benzene 
• 1127955-48-9 2-(2-bromobenzyl)-2-phenyl-1,3-dithiane 
• 536-74-3 phenylacetylene 
• 1341774-89-7 2-(2-bromophenyl)-2-hydroxy-1-phenylethan-1-one 
• 19472-74-3 2-(2-bromophenyl)acetonitrile 
• 100-58-3 phenylmagnesium bromide 
• 470710-06-6 2-(2-bromo-phenyl)-3-oxo-3-phenyl-propionitrile 

Downstream Products

• 55962-04-4 2-phenyl-2,3-dihydrobenzofuran 
• 772339-91-0 α-(o-bromophenylmethyl)-β,β-difluorostyrene 
• 1839-72-1 2-phenylbenzofuran 
• 4809-08-9 3-phenyl-isocoumarin 
• 1211900-55-8 (Z)-(1H)-3-phenyl-N-tert-butyl-1H-isochromen-1-imine 
• 52604-15-6 1-benzyl-2-phenyl-1H-indole 
• 36081-67-1 1-(2-bromophenyl)-2-phenyl-1,2-ethanedione 
• 948-65-2 2-phenyl-indole 

Relevant articles and documents

Tailoring the Molecular Properties with Isomerism Effect of AIEgens

It is challenging to achieve precise control on the properties of organic π-functional materials to widen their practical applications. On the other hand, the study of aggregation-induced emission luminogens (AIEgens) helps achieve such goals because of i

Intramolecular Anti-Carbolithiation of Alkynes: Stereo-Directing Effect of Lithium-Coordinating Substituents

This paper presents the results of our investigations on the stereochemical course of intramolecular carbolithiation of alkynes. It is shown that the presence of a lithium-chelating propargylic substituent completely reverses the otherwise favored syn-pro

Palladium-catalyzed synthesis of α-aryl acetophenones from styryl ethers and aryl diazonium saltsviaregioselective Heck arylation at room temperature

Preparation of α-aryl acetophenones from styryl ethers and aryldiazonium salts is described. The reaction is catalyzed by palladium acetate at room temperature in the absence of ligand and base. The developed method is highly attractive in terms of reaction conditions, substrate scope, functional group tolerance and yields. Synthetic applications of the present method are demonstrated by preparing α-aryl indoles and 3-aryl isocoumarin from styryl ethers.