168975-95-9Relevant articles and documents
Cationic Lipid
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Paragraph 0248-0249; 0270-0271, (2020/11/24)
The present invention provides a cationic lipid which is able to be used for nucleic acid delivery to the cytoplasm. A cationic lipid according to the present invention is, for example, a compound represented by formula (1) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 independently represent an alkylene group having 3 to 10 carbon atoms; R1 and R2 independently represent an alkyl group having 4 to 24 carbon atoms or an alkenyl group having 4 to 24 carbon atoms; R3 represents an alkyl group having 1 to 3 carbon atoms; and X1 represents a single bond or CO—O—.
PREPARATION OF HOMOLOGOUS PYRAZOLONEDICARBOXYLATES
Makarevic, Janja,Skaric, Vinko
, p. 1207 - 1218 (2007/10/02)
Homologous disodium pyrazolonedicarboxylates (8, 16f and 16g) as possible protectors of cis-DDP induced nephrotoxicity, have been prepared by the reaction of hydrazine with di-t-butyl ethyl β-keto triesters (5b, 13b and 13c) and subsequent hydrolysis of f