16899-54-0Relevant articles and documents
A novel method for the synthesis of 4(3H)-quinazolinones
Jing, Xiao-Bi,Li, Zhen,Pan, Xin,Shi, Yao-Cheng
, p. 1145 - 1149 (2008)
Different metal perchlorates were screened to catalyze the three-component reaction of anthranilic acid, triethyl orthoformate and amines to afford quinazolin-4(3H)-ones in solvent-free conditions. Ni(ClO4) 2 or Zn(ClO4)s
Dabco as a novel and efficient catalyst for the synthesis of 4(3H)-Quinazolinone derivatives
Heravi, Majid M.,Javanmardi, Najme,Oskooie, Hossein A.,Baghernejad, Bita
scheme or table, p. 305 - 308 (2012/04/17)
4(3H)-Quinazolinones were synthesized in high to excellent yields through the one-pot condensation of anthranilic acid, trimethyl orthoformate and primary amines in the presence of DABCO under solvent free conditions.
Synthesis and in vitro study of platelet antiaggregant activity of 1,2,3,4-tetrahydroquinazoline derivatives
Gravier,Dupin,Casadebaig,Hou,Boisseau,Bernard
, p. 531 - 535 (2007/10/02)
Some original 3-substituted 1,2,3,4-tetrahydroquinazolines were synthesized. Their antiplatelet activity was evaluated in vitro with respect to aggregation induced by the main inducers (ADP, collagen, arachidonic acid), platelet serotonin release reaction and thromboxane A2 synthesis. All these molecules possess an inhibiting power which, compared to that of aspirin in the same conditions, is the same or greater when aggregation is induced by ADP.
