169051-60-9

Basic information

• Product Name: L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT
• Synonyms: 3-sn-Phosphatidic acid, 1,2-dipalmitoyl monosodium salt, L-β,γ-Dipalmitoyl-α-phosphatidic acid monosodium salt;Hexadecanoic Acid (R)-1-[(Phosphonooxy)Methyl]-1,2-ethanediyl Ester, MonosodiuM Salt;Hexadecanoic Acid 1,1'-[(1R)-1-[(Phosphonooxy)Methyl]-1,2-ethanediyl] Ester SodiuM Salt;MonosodiuM 1,2-dipalMitoyl-sn-glycero-3-phosphate;DPPA L-4116;L-β,γ-Dipalmitoyl-α-phosphatidic acid monosodium salt;Phosphatidic Acid, Dipalmitoyl;16:0 PA
• CAS NO: 169051-60-9
• Molecular Formula: C35H67Na2O8P
• Molecular Weight: 692.85
• EINECS: 275-158-9
• Mol File: 169051-60-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 706.9°C at 760 mmHg
• Flash Point: 381.3°C
• Appearance: /
• Vapor Pressure: 7.15E-22mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT(169051-60-9)
• EPA Substance Registry System: L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT(169051-60-9)

Safety Data

• WGK Germany: 3
• F: 10-21
• Hazardous Substances Data: 169051-60-9(Hazardous Substances Data)

Usage

Description

L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT, also known as 1,2-Dipalmitoyl-sn-glycero-3-phosphate (DPPA), is a phospholipid containing the long-chain (16:0) palmitic acid inserted at the sn-1 and sn-2 positions. It plays a crucial role in the formation of phosphatidic acids, which are essential for intracellular and extracellular signaling. DPPA is used in the generation of micelles, liposomes, and artificial membranes, making it a versatile compound in various applications.

Uses

Used in Pharmaceutical Applications:
L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT is used as a component in the characterization of polymer-stabilized liposome systems for drug delivery. It aids in the encapsulation and controlled release of therapeutic agents, enhancing their efficacy and bioavailability.
Used in Medical Research:
In the study of amphotericin B-entrapping lipid nanoparticles, L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT is used to improve the in vitro and in vivo characteristics of these nanoparticles. This application helps in the development of more effective treatments for various diseases, particularly those requiring targeted drug delivery.
Used in Nanotechnology:
L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT is employed in the development of novel drug delivery systems, such as organic and metallic nanoparticles, to enhance the delivery, bioavailability, and therapeutic outcomes of various pharmaceutical compounds. This application contributes to the advancement of nanotechnology in the medical field.
Used in Biochemistry and Cell Biology:
As a phospholipid, L-BETA,GAMMA-DIPALMITOYL-ALPHA-PHOSPHATIDIC ACID DISODIUM SALT is used in the study of cell membrane structure and function, as well as in the investigation of intracellular and extracellular signaling pathways. This application provides valuable insights into cellular processes and the development of new therapeutic strategies.

InChI:InChI=1/C35H69O8P.2Na/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(36)41-31-33(32-42-44(38,39)40)43-35(37)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2;;/h33H,3-32H2,1-2H3,(H2,38,39,40);;/q;2*+1/p-2