169061-79-4

Basic information

• Product Name: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine
• Synonyms: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine
• CAS NO: 169061-79-4
• Molecular Weight: 790.005
• Mol File: 169061-79-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine(CAS DataBase Reference)
• NIST Chemistry Reference: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine(169061-79-4)
• EPA Substance Registry System: N^α-(9-fluorenylmethoxycarbonyl)-3-O-<3,4,6-tri-O-acetyl-2-deoxy-1-thio-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranosyl>-L-serine(169061-79-4)

Safety Data

• Hazardous Substances Data: 169061-79-4(Hazardous Substances Data)

Upstream product

• 122210-05-3 1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose 
• 73724-45-5 N-(9H-fluoren-9-ylmethoxycarbonyl)-L-serine 

Downstream Products

• 160067-63-0 N^α-(9-flourenylmethoxycarbonyl)-3-O-(2-acetamido-2-deoxy-3,4,6-tri-O-acetyl-Β-D-glucopyranosyl)-L-serine 

Relevant articles and documents

Preparation of Building Blocks for Glycopeptide Synthesis by Glycosylation of Fmoc Amino Acids Having Unprotected Carboxyl Groups

Nα-Fmoc amino acids with an unprotected α-carboxyl group have been glycosylated with carbohydrate 1,2-trans peracetates using Lewis acids as promoters.Aliphatic and phenolic O- and S-glycosides of amino acids, with a 1,2-trans anomeric configuration, were obtained as products in 34-65percent yields.The glycosylated building blocks have the protective groups of choice (i.e.O-acetyl and Nα-Fmoc) for direct use in stepwise synthesis of glycopeptides.The starting materials are readily available and the method does not require an extensive experience in synthetic carbohydrate chemistry.