169113-55-7Relevant articles and documents
Syntheses of (4,1-benzoxazepine-3-ylidene)acetic acid derivatives and their inhibition of squalene synthase
Miki, Takashi,Kori, Masakuni,Tozawa, Ryu-Ichi,Nakamura, Masahira,Sugiyama, Yasuo,Yukimasa, Hidefumi
, p. 53 - 58 (2002)
The (3,5-trans)-7-chloro-5-(2-chlorophenyl)-2-oxo-1,2,3,5-tetrahydro-4,1- benzoxazepine-3-acetic acid derivatives 1 have been previously identified as potent squalene synthase inhibitors. A series of (4,1-benzoxazepin-3-ylidene) acetic acid derivatives we