169128-06-7

Basic information

• Product Name: 12a-Chloro-3-(dimethylphenylsilanyl)-11-hydroxy-3-methyl-1,2,3,4,6,6a,12a,12b-octahydrobenzanthracene-7,12-dione
• CAS NO: 169128-06-7
• Molecular Weight: 465.064
• Mol File: 169128-06-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 12a-Chloro-3-(dimethylphenylsilanyl)-11-hydroxy-3-methyl-1,2,3,4,6,6a,12a,12b-octahydrobenzanthracene-7,12-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 12a-Chloro-3-(dimethylphenylsilanyl)-11-hydroxy-3-methyl-1,2,3,4,6,6a,12a,12b-octahydrobenzanthracene-7,12-dione(169128-06-7)
• EPA Substance Registry System: 12a-Chloro-3-(dimethylphenylsilanyl)-11-hydroxy-3-methyl-1,2,3,4,6,6a,12a,12b-octahydrobenzanthracene-7,12-dione(169128-06-7)

Upstream product

• 18855-92-0 3-chlorojuglone 
• 159692-35-0 (+/-)-5-(dimethylphenylsilanyl)-5-methyl-1-vinyl-1-cyclohexene 

Relevant articles and documents

Synthesis of Naturally (MM 47755; X-14881 E) and Non-Naturally Occuring Aromatic Angucyclinones

The Diels-Alder reactions of the naphthoquinones 1-4 with the dienes 5a-7 were investigated.The regioisomeric outcome of the adducts 10a-10g, 16, and 23 is in agreement with theoretical predictions from frontier orbital calculations.The adduct 10a was further converted to the non-natural (e.g. 15) and the adduct 16 to the natural angucyclinones MM 47755 (19a) and X-14881 E (22) by silicon-oxygen exchange and photooxygenation.The addition of naphthoquinones 2 and 4 to dienes 6 and 7 afford the Diels-Alder adducts 16 and 23, respectively, which are valuable intermediates for further transformation into non-aromatic angucyclinones. - Keywords: Angucyclinones / MM 47755 / X-14881 E / Diels-Alder reactions / Silicon-oxygen exchange