169137-67-1

Basic information

• Product Name: (4-benzyloxy-2-iodo-5-methoxyphenyl)methanol
• Synonyms: (4-benzyloxy-2-iodo-5-methoxyphenyl)methanol
• CAS NO: 169137-67-1
• Molecular Weight: 370.187
• Mol File: 169137-67-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (4-benzyloxy-2-iodo-5-methoxyphenyl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (4-benzyloxy-2-iodo-5-methoxyphenyl)methanol(169137-67-1)
• EPA Substance Registry System: (4-benzyloxy-2-iodo-5-methoxyphenyl)methanol(169137-67-1)

Safety Data

• Hazardous Substances Data: 169137-67-1(Hazardous Substances Data)

Upstream product

• 33693-48-0 4-benzyloxy-3-methoxybenzyl alcohol 
• 2426-87-1 3-methoxy-4-(phenylmethoxy)benzaldehyde 

Downstream Products

• 1383707-70-7 (E)-benzyl 2-[6-(benzyloxy)-5-methoxyisobenzofuran-1(3H)-ylidene]acetate 
• 1383707-69-4 (Z)-benzyl 2-[6-(benzyloxy)-5-methoxyisobenzofuran-1(3H)-ylidene]acetate 
• 1383707-43-4 (E)-methyl 2-[6-(benzyloxy)-5-methoxyisobenzofuran-1(3H)-ylidene]acetate 
• 1383707-42-3 (Z)-methyl 2-[6-(benzyloxy)-5-methoxyisobenzofuran-1(3H)-ylidene]acetate 
• 937168-05-3 3-[5'-benzyloxy-4'-methoxy-2'-(methoxymethoxymethyl)phenyl]-4-hydroxy-6,7-dimethoxychromen-2-one 
• 937168-04-2 3-[5'-benzyloxy-4'-methoxy-2'-(methoxymethoxymethyl)phenyl]-4-hydroxy-5,7-dimethoxychromen-2-one 
• 937168-03-1 3-[5'-benzyloxy-4'-methoxy-2'-(methoxymethoxymethyl)phenyl]-4-hydroxy-5,6,7-trimethoxychromen-2-one 
• 937167-97-0 5-benzyloxy-4-methoxy-2-(methoxymethoxymethyl)phenylboronic acid 
• 937167-94-7 4-benzyloxy-2-iodo-5-methoxy-1-(methoxymethoxymethyl)benzene 

Relevant articles and documents

Phosphine/palladium-catalyzed syntheses of alkylidene phthalans, 3-deoxyisoochracinic acid, isoochracinic acid, and isoochracinol

In this study we used sequential catalysis-PPh3-catalyzed nucleophilic addition followed by Pd(0)-catalyzed Heck cyclization-to construct complex functionalized alkylidene phthalans rapidly, in high yields, and with good stereoselectivities (E/Z ratios of up to 1:22). The scope of this Michael-Heck reaction includes substrates bearing various substituents around the alkylidene phthalan backbone. Applying this efficient sequential catalysis, we accomplished concise total syntheses of 3-deoxyisoochacinic acid, isoochracinic acid, and isoochracinol.