169158-03-6 Usage
Description
(2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID is a propanoic acid derivative with a molecular formula C17H23NO4. It features a vinylphenyl group and a tert-butoxy group, which serves as a protective group for controlled reactions. (2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID may have potential applications in organic synthesis, pharmaceuticals, and drug design due to its structural properties and potential biological activity.
Uses
Used in Pharmaceutical Industry:
(2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID is used as a building block for the development of new pharmaceutical compounds. Its unique structure allows for the creation of various drug candidates with potential therapeutic effects.
Used in Organic Synthesis:
(2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID is used as an intermediate in the synthesis of complex organic molecules. Its vinylphenyl group can be further modified or reacted with other molecules to form a wide range of compounds with different properties and applications.
Used in Drug Design:
(2S)-2-[(TERT-BUTOXY)CARBONYLAMINO]-3-(4-VINYLPHENYL)PROPANOIC ACID is used as a starting material in the design of new drugs. Its structural properties and potential biological activity make it a promising candidate for the development of innovative therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 169158-03-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,1,5 and 8 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 169158-03:
(8*1)+(7*6)+(6*9)+(5*1)+(4*5)+(3*8)+(2*0)+(1*3)=156
156 % 10 = 6
So 169158-03-6 is a valid CAS Registry Number.
169158-03-6Relevant articles and documents
C-H Olefination of Tryptophan Residues in Peptides: Control of Residue Selectivity and Peptide-Amino Acid Cross-linking
Terrey, Myles J.,Holmes, Ashley,Perry, Carole C.,Cross, Warren B.
, p. 7902 - 7907 (2019)
There is high demand for new methods to modify peptides, for application in drug discovery and biomedicine. A C-H functionalization protocol for the olefination of tryptophan residues in peptides is described. The modification is successful for Trp residues at any position in the peptide, has broad scope in the styrene coupling partner, and offers opportunities for conjugating peptides with other biomolecules. For peptides containing both Trp and Phe, directing group manipulation enables full control of residue selectivity.
Novel non-peptide GPIIb/IIIa antagonists: Synthesis and biological activities of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl] acetic acids
Kitamura,Fukushi,Miyawaki,Kawamura,Terashita,Sugihara,Naka
, p. 258 - 267 (2007/10/03)
To improve the in vitro and in vivo potency of our first low molecular weight GPIIb/IIIa antagonist 1 (TAK-029), a series of 2-[4-[2-(4-amidinobenzoylamino)-2-(substituted)acetyl]-3-(2-methoxy-2- oxoethyl)-2-oxopiperazinyl]acetic acids were synthesized th
