169186-38-3

Basic information

• Product Name: (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide
• Synonyms: (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide
• CAS NO: 169186-38-3
• Molecular Weight: 501.003
• Mol File: 169186-38-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide(169186-38-3)
• EPA Substance Registry System: (RS)-2-(4-chlorobenzenesulfonylamino)-N-(4-(2-methoxycarbonylethyl)phenyl)-3-phenylpropanamide(169186-38-3)

Safety Data

• Hazardous Substances Data: 169186-38-3(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 40279-97-8 (RS)-2-(4-chlorobenzenesulfonylamino)-3-phenylpropanoic acid 
• 83528-15-8 methyl 2-(4-aminophenyl)propanoate hydrochloride 

Downstream Products

• 169186-80-5 (RS)-N-(4-(2-carboxyethyl)phenyl)-2-(4-chlorobenzenesulfonylamino)-3-phenylpropanamide 

Relevant articles and documents

Arylsulfonamide derivative and pharmaceutical compositions and use thereof

An arylsulfonamide derivative of the formula (I): STR1 wherein R1 is unsubstituted phenyl or naphthyl, or phenyl substituted by 1 to 3 same or different substituents selected from the group consisting of halogen, alkyl, nitro and alkoxy, R2 is straight, branched, or branched cyclic alkyl with 1 to 15 carbon atoms, phenyl, phenyloxyl, phenyloxy substituted by one or more halogen atoms, cycloalkyl with 5 to 7 carbon atoms, indolyl, alkylthiol with 1 to 4 carbon atoms, hydroxyl, protected hydroxyl, imidazolyl, pyridyloxyl, or --OSO2 R4, R4 is straight or branched alkyl with 1 to 15 carbon atoms, or unsubstituted phenyl or thienyl, or phenyl or thienyl substituted by 1 to 3 same or different substituents of halogen, alkyl, nitro and alkoxy, R3 is hydrogen or straight or branched alkyl with 1 to 20 carbon atoms, n is an integer of 0 to 10, p is an integer of 0 to 10, X is a group of the formula m and q are independently an integer of 0 to 8, and A is a direct bond or phenylene, or a salt thereof; a process for manufacture thereof and a pharmaceutical composition containing same. The above compound exhibits thromboxane A2 antagonism.