169280-10-8

Basic information

• Product Name: [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester
• Synonyms: [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester
• CAS NO: 169280-10-8
• Molecular Weight: 260.333
• Mol File: 169280-10-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester(169280-10-8)
• EPA Substance Registry System: [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester(169280-10-8)

Safety Data

• Hazardous Substances Data: 169280-10-8(Hazardous Substances Data)

Usage

Description

[4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester is a chemical compound with the molecular formula C17H20O3. It is an ethyl ester derivative of [4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid, characterized by its white to off-white crystalline solid appearance and solubility in organic solvents such as ethanol and ethyl acetate.

Uses

Used in Pharmaceutical Industry:
[4-(cyclopropylcarbonyl)]-α-α-dimethylbenzeneacetic acid ethyl ester is used as a pharmaceutical intermediate for the synthesis of various drugs and pharmaceutical compounds. Its role in the production of active pharmaceutical ingredients makes it a crucial component in pharmaceutical research and development.
Used in Drug Synthesis:
This chemical compound is used as a key building block in the synthesis of medications, contributing to the development of new and improved pharmaceutical products. Its versatility in chemical reactions allows for the creation of a wide range of therapeutic agents.

Upstream product

• 169280-22-2 2-(4-cyclopropanecarbonyl-phenyl)-2-methyl-propionamide 
• 162096-53-9 2-[3-(4-Chloro-butyryl)-phenyl]-2-methyl-propionic acid, ethyl ester 
• 76811-97-7 4-(4-chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic acid ethyl ester 
• 7623-11-2 2-chlorobutyryl chloride 
• 4635-59-0 4-Chlorobutanoyl chloride 
• 35981-86-3 (4-Cyclopropanecarbonyl-phenyl)-acetic acid, ethyl ester 
• 74-87-3 methylene chloride 
• 169280-07-3 para-(4-chloro-1-oxobutyl)benzene acetic acid ethyl ester 
• 64-17-5 ethanol 

Downstream Products

• 76811-97-7 4-(4-chloro-1-oxobutyl)-α,α-dimethylbenzeneacetic acid ethyl ester 
• 76812-02-7 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-α,α-dimethylbenzeneacetic acid ethyl ester 

Relevant articles and documents

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula whereinW represents —C(=O)— or —CH(OH)—;R1 represents hydrogen or hydroxy;R2 represents hydrogen;R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2;n is an integer of from 1 to 5;m is an integer 0 or 1;R3 is —COOH or —COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof,with the proviso that where R1 and R2 are taken together to form a second bond between the carbon atoms bearing R1 and R2 or where R1 represented hydroxy, m is an integer 0.

Antihistaminic piperidine derivatives and intermediates for the preparation thereof

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof.whereinR1 is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched;R2 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; orstereoisomers or pharmaceutically acceptable acid addition salt thereof.

Intermediates useful for the preparation of antihistaminic piperidine derivatives

The present invention is related to a novel intermediates and processes which are useful in the preparation of certain antihistaminic piperidine derivatives of the formula wherein W represents -C(=O)- or -CH(OH)-; R1 represents hydrogen or hydroxy; R2 represents hydrogen; R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2; n is an integer of from 1 to 5; m is an integer 0 or 1; R3 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched each of A is hydrogen or hydroxy; and pharmaceutically acceptable salts and individual optical isomers thereof, with the proviso that where R1 and R2 are ta to form a second bond between the carbon R1 and R2 or where R1 represented hydroxy integer 0.