16947-86-7

Basic information

• Product Name: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID
• Synonyms: BOC-(S)-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID;(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID;(S)-3-((tert-Butoxycarbonyl)aMino)-2-(4-MethylphenylsulfonaMido)propanoic acid
• CAS NO: 16947-86-7
• Molecular Formula: C₁₅H₂₂N₂O₆S
• Molecular Weight: 358.41
• Mol File: 16947-86-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Store at 0-5°C
• CAS DataBase Reference: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(16947-86-7)
• EPA Substance Registry System: (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID(16947-86-7)

Safety Data

• Hazardous Substances Data: 16947-86-7(Hazardous Substances Data)

Usage

Description

(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID, also known as Boc-Amino-PTS, is a chemical compound that serves as a crucial building block in the synthesis of peptides and pharmaceuticals. It is a derivative of (S)-2-Amino-3-(p-toluenesulfonamido)propionic acid and is widely recognized for its role in solid-phase peptide synthesis. Boc-Amino-PTS is an essential reagent for the protection of amino acids during peptide synthesis, ensuring the successful formation of the desired peptide sequences. This white to off-white crystalline powder should be stored in a cool, dry place away from light and moisture to maintain its stability and reactivity.

Uses

Used in Pharmaceutical Industry:
(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID is used as a key building block for the synthesis of various peptides and pharmaceuticals. Its application is primarily driven by its ability to protect amino acids during the peptide synthesis process, which is crucial for the successful creation of specific peptide sequences and the development of targeted therapeutic agents.
Used in Research and Development:
In the realm of research and development, Boc-Amino-PTS is employed as an important reagent for the protection of amino acids during peptide synthesis. This protection is vital for the accurate and efficient synthesis of complex peptide structures, which are often the focus of cutting-edge research in drug discovery and development. (S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID's role in safeguarding amino acids allows researchers to explore new peptide-based therapeutic strategies and advance the field of peptide chemistry.
Used in Solid-Phase Peptide Synthesis:
(S)-BOC-3-AMINO-2-(P-TOLUENESULFONYLAMINO)-PROPIONIC ACID is used as a protective agent for amino acids in solid-phase peptide synthesis. This technique is a widely utilized method for the production of peptides, where Boc-Amino-PTS ensures the selective protection of amino groups, preventing unwanted side reactions and facilitating the stepwise assembly of the desired peptide sequence. Its application in this process is essential for the efficient and reliable synthesis of peptides with specific biological activities and potential pharmaceutical applications.

Upstream product

• 1070-19-5 N-(tert-butyloxycarbonyl) azide 
• 21753-19-5 2-(S)-p-toluenesulfonylamino-β-alanine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 36212-66-5 N²-(toluene-4-sulfonyl)-L-asparagine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 16947-84-5 N-[(benzyloxy)carbonyl]-3-[(tert-butoxycarbonyl)amino]-L-alanine 
• 78089-13-1 (S)-2-(2,3-Bis-benzyloxy-benzoylamino)-3-tert-butoxycarbonylamino-propionic acid 
• 96845-94-2 ethyl N²-<4-<<(benzyloxy)carbonyl>methylamino>benzoyl>-N³-<(1,1-dimethylethoxy)carbonyl>-2,3-diaminopropanoic acid 
• 74536-29-1 (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoic acid 
• 169604-92-6 (S)-3-tert-Butoxycarbonylamino-2-(toluene-4-sulfonylamino)-propionic acid methyl ester 
• 80312-73-8 (S)-3-amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 80312-88-5 tert-butyl 2S-(3-hydroxy-2-((4-methylphenyl)sulfonamido)propyl)carbamate 
• 199853-74-2 4-Methyl-N-[(R)-1-methyl-4-(3-methyl-benzyl)-[1,4]diazepan-6-yl]-benzenesulfonamide 
• 199853-73-1 4-Methyl-N-[(R)-4-methyl-1-(3-methyl-benzyl)-2-oxo-[1,4]diazepan-6-yl]-benzenesulfonamide 
• 199853-72-0 (S)-N-methyl-N-[3-(3-methylbenzyl)-amino-2-(4-toluenesulfonyl)amino-1-propyl]aminoacetic acid 
• 199853-76-4 N-[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-2-methylamino-N-(3-methyl-benzyl)-acetamide 
• 199853-70-8 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetylaminomethyl]-1-(4-toluenesulfonyl)aziridine 
• 199853-69-5 (S)-3-[N-(3-methylbenzyl)-N-trifluoroacetyl]amino-2-(4-toluenesulfonyl)amino-1-propanol 
• 199853-67-3 {[[(S)-3-Hydroxy-2-(toluene-4-sulfonylamino)-propyl]-(3-methyl-benzyl)-carbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester 

Relevant articles and documents

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