169516-55-6

Basic information

• Product Name: 4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine
• Synonyms: 4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine;((2R,3R,4S,5R)-3-(Benzoyloxy)-5-(4-chloro-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-4-fluorotetrahydrofuran-2-yl)methyl benzoate
• CAS NO: 169516-55-6
• Molecular Formula: C₂₅H₁₉ClFN₃O₅
• Molecular Weight: 495.8868632
• Mol File: 169516-55-6.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine(169516-55-6)
• EPA Substance Registry System: 4-Chloro-7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-7H-pyrrolo[2.3-d]pyriMidine(169516-55-6)

Safety Data

• Hazardous Substances Data: 169516-55-6(Hazardous Substances Data)

Upstream product

• 97614-44-3 2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide 
• 3680-69-1 4-chloro-1H-pyrrolo[2,3-d]pyrimidine 
• 97614-43-2 1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose 
• 98855-71-1 ((2R,3R,4S)-3-(benzoyloxy)-5-bromo-4-fluorotetrahydrofuran-2-yl)methyl benzoate 
• 7400-05-7 6-amino-5-(2,2-diethoxyethyl)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 
• 67831-84-9 2-thioxo-1,2,3,7-tetrahydro-4H-pyrrolo[2,3-d]pyrimidin-4-one 
• 3680-71-5 1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one 
• 52133-67-2 ethyl 2-cyano-4,4-diethoxybutyrate 

Downstream Products

• 169516-60-3 4-chloro-7-(2'-deoxy-2'-fluoro-β-D-arabinofuranosyl)pyrrolo<2,3-d>pyrimidine 
• 1289376-76-6 C₂₅H₁₇Cl₂FN₆O₅ 
• 1289376-75-5 C₁₈H₁₃ClFIN₆O₃ 
• 1345193-51-2 C₁₈H₁₂ClF₂IN₆O₃ 
• 1345193-54-5 C₂₅H₁₆Cl₂F₂N₆O₅ 
• 1338072-77-7 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-(thiophen-3-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-75-5 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-(furan-3-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-82-4 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-methyl-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-69-7 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-(furan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-72-2 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-(thiophen-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-79-9 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-(thiazol-2-yl)-7H-pyrrolo[2,3-d]pyrimidine 
• 1338072-67-5 7-(3,5-di-O-benzoyl-2-deoxy-2-fluoro-β-D-arabinofuranosyl)-4-phenyl-7H-pyrrolo[2,3-d]pyrimidine 

Relevant articles and documents

CYCLIC DINUCLEOTIDES AS ANTICANCER AGENTS

The present invention is directed to compounds of the formulae I, II and III as shown below wherein all substituents are defined herein, as well as pharmaceutically acceptable compositions comprising compounds of the invention and methods of using said compositions in the treatment of various disorders.

ANTIVIRAL AGENTS

Compounds of structural formula (I): and pharmaceutically acceptable salts thereof; as defined herein, are described for use in the prevention and/or treatment of HCV infections. Novel compounds of the formula (I) and pharmaceutical formulations containin

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The use of a late-stage selective Staudinger reaction in the preparation of the novel HCV RNA polymerase inhibitor is described. Georg Thieme Verlag Stuttgart - New York.