169555-95-7 Usage
Description
Fmoc-3-(4-pyridyl)-L-alanine, also known as Fmoc-?-(4-pyridyl)-Ala-OH, is a light yellow powder with unique chemical properties. It is a derivative of L-alanine, an essential amino acid, and is modified with a 9-fluorenylmethoxycarbonyl (Fmoc) group and a 4-pyridyl group. This modification enhances its reactivity and utility in various applications, particularly in the field of peptide synthesis.
Uses
Used in Pharmaceutical Industry:
Fmoc-3-(4-pyridyl)-L-alanine is used as a building block for the solid phase peptide synthesis (SPPS) technique. Its incorporation into peptide sequences allows for the creation of novel bioactive peptides with potential applications in drug development, targeting various diseases and conditions.
Used in Research and Development:
In the field of research and development, Fmoc-3-(4-pyridyl)-L-alanine serves as a valuable compound for the synthesis of custom peptides and peptide analogs. These synthesized peptides can be used for studying protein-protein interactions, enzyme inhibition, and other biological processes, contributing to the advancement of scientific knowledge and the development of new therapeutic strategies.
Used in Chemical Synthesis:
Fmoc-3-(4-pyridyl)-L-alanine can also be utilized in chemical synthesis for the creation of various organic compounds and materials. Its unique structure and reactivity make it a versatile building block for the development of new molecules with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.
Check Digit Verification of cas no
The CAS Registry Mumber 169555-95-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,5,5 and 5 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 169555-95:
(8*1)+(7*6)+(6*9)+(5*5)+(4*5)+(3*5)+(2*9)+(1*5)=187
187 % 10 = 7
So 169555-95-7 is a valid CAS Registry Number.
InChI:InChI=1/C23H20N2O4/c26-22(27)21(13-15-9-11-24-12-10-15)25-23(28)29-14-20-18-7-3-1-5-16(18)17-6-2-4-8-19(17)20/h1-12,20-21H,13-14H2,(H,25,28)(H,26,27)/t21-/m0/s1
169555-95-7Relevant articles and documents
Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives
Moussa, Amer,Meffre, Patrick,Martinez, Jean,Rolland, Valerie
, p. 1339 - 1348 (2012/09/07)
Enantiomerically pure 2-, 3- or 4-pyridylalanine (pya) and 2-azatyrosine (azatyr) are known to present various biological activities. After incorporation into appropriate peptide sequences, these heterocyclic non natural α-amino acids could behave as new substrates or inhibitors of elastase from Pseudomonas aeruginosa. This enzyme is known to be involved in nosocomial infections and infections related to the cystic fibrosis disease. New efficient chemoenzymatic preparations of those compounds using α-chymotrypsin (α-CT) are presented. Springer-Verlag 2011.
