169616-12-0

Basic information

• Product Name: dimethyl 3,4-ethylenedioxypyrrole-2,5-dicarboxylate
• Synonyms: dimethyl 3,4-ethylenedioxypyrrole-2,5-dicarboxylate
• CAS NO: 169616-12-0
• Molecular Weight: 241.2
• Mol File: 169616-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: dimethyl 3,4-ethylenedioxypyrrole-2,5-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 3,4-ethylenedioxypyrrole-2,5-dicarboxylate(169616-12-0)
• EPA Substance Registry System: dimethyl 3,4-ethylenedioxypyrrole-2,5-dicarboxylate(169616-12-0)

Safety Data

• Hazardous Substances Data: 169616-12-0(Hazardous Substances Data)

Upstream product

• 6096-81-7 dimethyl iminodiacetate 

Downstream Products

• 169616-17-5 3,4-ethylenedioxypyrrole 
• 169616-13-1 3,4-ethylenedioxypyrrole-2,5-dicarboxylic acid 

Relevant articles and documents

3,4-Dialkoxypyrroles and 2,3,7,8,12,13,17,18-octaalkoxyporphyrins

A five-step general synthesis of 3,4-dialkoxypyrroles 7c-f is described starting with the condensation of dimethyl N-benzyliminodiacetate (1 b) and diethyl oxalate to give dimethyl 1-benzyl-3,4-dihydroxypyrrole-2,5-dicarboxylate (2b), which is bis-O-alkylated to the corresponding 3,4-diethers 3c-g. Pyrrole N-benzyl cleavage followed by ester hydrolysis and decarboxylation leads to 7c-f in 10-50% overall yield. Pyrroles 7c-f react with formaldehyde or benzaldehydes to give meso-H- (8a-d) or meso-tetraaryloctaalkoxyporphyrins 9a-g in moderate yields.