1696392-11-6 Usage
Description
1-[(2'-carbaMoylbiphenyl-4-yl) Methyl]-2-ethoxybenziMidazole-7-carboxylic acid is a complex organic compound with a unique chemical structure. It is characterized by its carbamoylbiphenyl and ethoxybenzimidazole moieties, which contribute to its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
1-[(2'-carbaMoylbiphenyl-4-yl) Methyl]-2-ethoxybenziMidazole-7-carboxylic acid is used as an intermediate in the synthesis of various pharmaceutical compounds. Its unique structure allows it to be a key component in the development of new drugs with specific therapeutic properties.
Used in Chemical Synthesis:
1-[(2'-carbaMoylbiphenyl-4-yl) Methyl]-2-ethoxybenziMidazole-7-carboxylic acid is used as a building block in the synthesis of complex organic molecules. Its versatile structure makes it a valuable asset in the creation of novel compounds for various applications, including materials science and specialty chemicals.
Used in Research and Development:
1-[(2'-carbaMoylbiphenyl-4-yl) Methyl]-2-ethoxybenziMidazole-7-carboxylic acid serves as a valuable research tool in the study of chemical reactions and mechanisms. Its unique structure allows scientists to explore new reaction pathways and develop innovative synthetic strategies.
Used in Azilsartan Kamedoxomil Preparation:
1-[(2'-carbaMoylbiphenyl-4-yl) Methyl]-2-ethoxybenziMidazole-7-carboxylic acid is used as an intermediate in the preparation of azilsartan kamedoxomil, which is an angiotensin II receptor blocker. This application highlights its importance in the development of medications for the treatment of hypertension and other cardiovascular conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1696392-11-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,9,6,3,9 and 2 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1696392-11:
(9*1)+(8*6)+(7*9)+(6*6)+(5*3)+(4*9)+(3*2)+(2*1)+(1*1)=216
216 % 10 = 6
So 1696392-11-6 is a valid CAS Registry Number.
1696392-11-6Relevant articles and documents
Liquid chromatography/tandem mass spectrometry study of forced degradation of azilsartan medoxomil potassium
Swain, Debasish,Patel, Prinesh N.,Palaniappan, Ilayaraja,Sahu, Gayatri,Samanthula, Gananadhamu
, p. 1437 - 1447 (2015/07/15)
Rationale Azilsartan medoxomil potassium (AZM) is a new antihypertensive drug introduced in the year 2011. The presence of degradation products not only affects the quality, but also the safety aspects of the drug. Thus, it is essential to develop an efficient analytical method which could be useful to selectively separate and identify the degradation products of azilsartan medoxomil potassium. Methods AZM was subjected to forced degradation under hydrolytic (acid, base and neutral), oxidative, photolytic and thermal stress conditions. Separation of the drug and degradation products was achieved by a liquid chromatography (LC) method using an Acquity UPLC C18 CSH column with mobile phase consisting of 0.02% trifluoroacetic acid and acetonitrile using a gradient method. Identification and characterization of the degradation products was carried out using LC/electrospray ionization quadrupole time-of-flight mass spectrometry (ESI-QTOFMS). Results A total of five degradation products (DP 1 to DP 5) were formed under various stress conditions and their structures were proposed with the help of tandem mass spectrometry (MS/MS) experiments and accurate mass data. A common degradation product (DP 4) was observed under all the degradation conditions. DP 1, DP 2 and DP 5 were observed under acid hydrolytic conditions whereas DP 3 was observed under alkaline conditions. Conclusions AZM was found to degrade under hydrolytic, oxidative and photolytic stress conditions. The structures of all the degradation products were proposed. The degradation pathway for the formation of degradation products was also hypothesized. A selective method was developed to quantify the drug in the presence of degradation products which is useful to monitor the quality of AZM.
