16965-72-3 Usage
Description
[(dimethoxyphosphoryl)(phenyl)methylidene]diazenium is a chemical compound that features a diazeniumdiolate group attached to a dimethoxyphosphoryl and a phenylmethylidene group. This unique structure and reactivity make it a promising candidate for applications in organic synthesis and pharmaceuticals. [(dimethoxyphosphoryl)(phenyl)methylidene]diazenium's diazeniumdiolate group has the potential to act as a nitric oxide donor, which could lead to the development of new nitric oxide-based therapeutics. Furthermore, the dimethoxyphosphoryl and phenylmethylidene groups contribute to its versatility as a building block for the synthesis of complex organic molecules.
Uses
Used in Organic Synthesis:
[(dimethoxyphosphoryl)(phenyl)methylidene]diazenium is used as a versatile building block for the synthesis of complex organic molecules due to its unique chemical structure and reactivity.
Used in Pharmaceutical Development:
[(dimethoxyphosphoryl)(phenyl)methylidene]diazenium is used as a potential candidate for developing new nitric oxide-based therapeutics, as its diazeniumdiolate group can act as a nitric oxide donor.
Used in Research and Development:
[(dimethoxyphosphoryl)(phenyl)methylidene]diazenium is used as a subject of further research to explore its reactivity and potential applications in various chemical and biomedical fields, with the aim of uncovering its full potential.
Check Digit Verification of cas no
The CAS Registry Mumber 16965-72-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,9,6 and 5 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16965-72:
(7*1)+(6*6)+(5*9)+(4*6)+(3*5)+(2*7)+(1*2)=143
143 % 10 = 3
So 16965-72-3 is a valid CAS Registry Number.
16965-72-3Relevant articles and documents
Rh(I)-Catalyzed Arylation of α-Diazo Phosphonates with Aryl Boronic Acids: Synthesis of Diarylmethylphosphonates
Zhou, Yujing,Zhang, Yan,Wang, Jianbo
, p. 621 - 627 (2017)
An efficient synthetic method for diarylmethylphosphonates is presented. A series of phosphonate derivatives with diverse functional groups can be accessed via a rhodium catalyzed cross-coupling reaction between α-diazo phosphonates and aryl boronic acids. Migratory insertion of rhodium carbene intermediates is postulated to be the critical step in this transformation.
Synthesis of α-Aryldiazophosphonates via a Diazo Transfer Reaction
Beletskaya, Irina P.,Titanyuk, Igor D.
, p. 2748 - 2757 (2022/03/14)
The simple synthetic procedure for preparation of α-aryl-α-diazophosphonates via a diazo transfer reaction is proposed. Benzylphosphonates reacted with tosyl azide (TsN3) in the presence of potassium tert-butoxide (KOtBu) to afford diazophosphonates in a yield up to 79%. The proposed method is general. The reaction uses easily available starting materials, tolerates various functional groups, and may be applied for multi-gram scale synthesis.
A removable functional group strategy for regiodivergent Wittig rearrangement products
Alam, Md Nirshad,Lakshmi,Maity, Pradip
supporting information, p. 8922 - 8926 (2018/12/10)
[1,2] and [2,3] Wittig rearrangements are competing reaction pathways, often leading to uncontrollable product distribution. We employ a single removable functional group to fulfill the dual role of attaining a reversible [2,3] and stabilizing radical int
