169772-26-3

Basic information

• Product Name: 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid
• Synonyms: 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid
• CAS NO: 169772-26-3
• Molecular Weight: 249.31
• Mol File: 169772-26-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid(169772-26-3)
• EPA Substance Registry System: 2-[(2,6-diisopropylphenyl)amino]-2-oxoacetic acid(169772-26-3)

Safety Data

• Hazardous Substances Data: 169772-26-3(Hazardous Substances Data)

Upstream product

• 42022-53-7 methyl 2-((2,6-diisopropylphenyl)amino)-2-oxoacetate 
• 609798-47-2 ethyl 2-((2,6-diisopropylphenyl)amino)-2-oxoacetate 
• 24544-04-5 2,6-diisopropylbenzenamine 

Downstream Products

• 28178-42-9 2,6-diisopropylphenyl isocyanate 
• 1643961-87-8 N¹-(4-bromo-2,6-diisopropylphenyl)-N²-(2,6-diisopropylphenyl)-oxalamide 
• 1643961-88-9 N-(4-bromo-2,6-diisopropylphenyl)-N'-(2,6-diisopropylphenyl)ethane-1,2-diamine 
• 1643962-07-5 1-(4-formyl-2,6-diisopropylphenyl)-3-(2,6-diisopropylphenyl)-4,5-dihydro-1H-imidazol-3-ium bromide 
• 1643962-01-9 1-(4-ethynyl-2,6-diisopropylphenyl)-3-(2,6-diisopropylphenyl)imidazolidine 
• 1643961-98-1 1-{2,6-diisopropyl-4-[(trimethylsilyl)ethynyl]phenyl}-3-[(2,6-diisopropylphenyl)imidazolidine] 
• 1643962-00-8 1-(4-formyl-2,6-diisopropylphenyl)-3-(2,6-diisopropylphenyl)imidazolidine 
• 1643961-99-2 1-(2,6-diisopropyl-4-vinylphenyl)-3-(2,6-diisopropylphenyl)imidazolidine 
• 1643962-13-3 1-[2,6-diisopropyl-4-(trimethylsilyl)phenyl]-3-(2,6-diisopropylphenyl)imidazolidine 
• 1643961-90-3 1-(4-bromo-2,6-diisopropylphenyl)-3-(2,6-diisopropylphenyl)imidazolidine 
• 868593-29-7 N-(2,6-diisopropylphenyl)-N'-(2,4,6-trimethoxyphenyl)oxalamide 
• 868593-27-5 N-(2,6-diisopropylphenyl)-N'-(2,4,6-trifluorophenyl)oxalamide 
• 868593-23-1 N-(2,6-diisopropylphenyl)-N'-(2,6-diethylphenyl)oxalamide 

Relevant articles and documents

Application of High-Throughput Competition Experiments in the Development of Aspartate-Directed Site-Selective Modification of Tyrosine Residues in Peptides

Herein we report a Cu-catalyzed, site-selective functionalization of peptides that employs an aspartic acid (Asp) as a native directing motif, which directs the site of O-arylation at a proximal tyrosine (Tyr) residue. Through a series of competition studies conducted in high-throughput reaction arrays, effective conditions were identified that gave high selectivity for the proximal Tyr in Asp-directed Tyr modification. Good levels of site-selectivity were achieved in the O-arylation at a proximal Tyr residue in a number of cases, including a peptide-small molecule hybrid.

Reactivity of Carbamoyl Radicals. A New, General, Convenient Free-Radical Synthesis of Isocyanates from Monoamides of Oxalic Acid

A new, general, simple synthesis of isocyanates was developed by oxidation of monoamides of oxalix acid with peroxydisulfate catalyzed by Ag and Cu salts.The reaction was carried out in a two-phase system (water and an organic solvent), and it is suitable also for practical applications, due to the simple experimental conditions and the inexpensive as well as nontoxic reagents.The first example of homolytic intramolecular aromatic carbamoylation is also reported.