169783-76-0 Usage
Description
D-[3-2H]RIBOSE, also known as deuterated ribose, is a stable isotope-labeled compound derived from the natural sugar ribose. It contains deuterium, a non-radioactive isotope of hydrogen, which makes it useful for various scientific applications. The expression is: D-[3-2H]RIBOSE is a deuterated form of ribose, a sugar molecule, which is labeled with deuterium atoms.
Uses
Used in Pharmaceutical Industry:
D-[3-2H]RIBOSE is used as a stable isotope tracer for studying metabolic pathways and enzyme mechanisms in the pharmaceutical industry. The use of deuterated compounds allows researchers to track the movement and transformation of molecules within biological systems without the complications of radioactivity.
Used in Biochemical Research:
D-[3-2H]RIBOSE is used as a research tool in biochemical research to investigate the structure and function of ribose-containing biomolecules, such as nucleic acids and other ribose-based compounds. The deuterium labeling provides a unique signature that can be detected and analyzed using various analytical techniques, such as mass spectrometry.
Used in NMR Spectroscopy:
D-[3-2H]RIBOSE is used as a NMR (Nuclear Magnetic Resonance) spectroscopy probe to study the interactions between ribose and other molecules, such as proteins or other sugars. The deuterium atoms in D-[3-2H]RIBOSE can provide additional information about the molecular environment and help to elucidate the details of molecular interactions.
Used in Isotope Labeling:
D-[3-2H]RIBOSE is used for isotope labeling in various scientific studies, including metabolic studies, enzyme kinetics, and drug development. The incorporation of deuterium into ribose allows for the differentiation between labeled and unlabeled molecules, providing valuable insights into biological processes and the effects of potential therapeutic compounds.
Used in Chemical Synthesis:
D-[3-2H]RIBOSE can be used as a starting material or intermediate in the chemical synthesis of deuterated ribose-containing compounds. This can be particularly useful in the development of deuterated drugs or other bioactive molecules, where the deuterium labeling may provide improved pharmacokinetic properties or reduced side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 169783-76-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,9,7,8 and 3 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 169783-76:
(8*1)+(7*6)+(6*9)+(5*7)+(4*8)+(3*3)+(2*7)+(1*6)=200
200 % 10 = 0
So 169783-76-0 is a valid CAS Registry Number.
169783-76-0Relevant articles and documents
Preparation of specifically deuterated RNA for NMR studies using a combination of chemical and enzymatic synthesis
Tolbert, Thomas J.,Williamson, James R.
, p. 7929 - 7940 (2007/10/03)
The syntheses of ATP, GTP, UTP, and CTP with deuterium labels on the 3', 4', and 5' carbons (2-5) is described. A combination of chemical and enzymatic synthesis is used where D,L-ribose-3,4,5,5'-d4 (±1) is first produced from glycerol-d8
