169787-82-0

Basic information

• Product Name: (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid
• Synonyms: (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid
• CAS NO: 169787-82-0
• Molecular Weight: 445.472
• Mol File: 169787-82-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid(169787-82-0)
• EPA Substance Registry System: (2'S,4'R)-4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic acid(169787-82-0)

Safety Data

• Hazardous Substances Data: 169787-82-0(Hazardous Substances Data)

Upstream product

• 95260-60-9 (2S,4S)-benzyl 4-benzyl-5-oxo-2-phenyloxazolidine-3-carboxylate 
• 169787-81-9 (2S,4R)-4-Benzhydryloxycarbonylmethyl-4-benzyl-5-oxo-2-phenyl-oxazolidine-3-carboxylic acid benzyl ester 

Downstream Products

• 169787-98-8 (4'R,E)-(-)-ethyl (4'-benzyl-4'-benzyloxycarbonylamino-5'-oxotetrahydrofuran-2'-ylidene)acetate 
• 169787-87-5 {(R)-3-Benzyl-3-benzyloxycarbonylamino-5-[1-ethoxycarbonyl-meth-(E)-ylidene]-2-oxo-pyrrolidin-1-yl}-acetic acid 
• 169787-86-4 {(R)-3-Benzyl-3-benzyloxycarbonylamino-5-[1-ethoxycarbonyl-meth-(E)-ylidene]-2-oxo-pyrrolidin-1-yl}-acetic acid tert-butyl ester 
• 1052203-23-2 (S)-2-((R)-4-Benzyl-4-benzyloxycarbonylamino-2-ethoxycarbonylmethyl-2-hydroxy-5-oxo-pyrrolidin-1-yl)-propionic acid methyl ester 
• 1052641-26-5 {(R)-4-Benzyl-4-benzyloxycarbonylamino-1-[(ethoxycarbonylmethyl-carbamoyl)-methyl]-2-hydroxy-5-oxo-pyrrolidin-2-yl}-acetic acid ethyl ester 
• 169787-91-1 (5R)-ethyl hydrogen 5-benzyl-5-benzyloxycarbonylamino-3-oxo-2-(triphenylphosphoranylidene)hexanedioate 
• 169873-64-7 (2'S,4'R)-(-)-4-(4'-benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-yl)-3-oxo-2-(triphenylphosphoranylidene)butanoate 
• 169787-93-3 (4'R,Z)-(-)-ethyl (4'-benzyl-4'-benzyloxycarbonylamino-5-oxotetrahydrofuran-2'-ylidene)bromoacetate 
• 169787-94-4 (4'R,E)-(-)-ethyl (4'-benzyl-4'-benzyloxycarbonylamino-5-oxotetrahydrofuran-2'-ylidene)bromoacetate 
• 187345-48-8 (R)-2-Acetylamino-4-methyl-pentanoic acid ((R)-3-benzyl-1-benzyloxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 187345-45-5 (S)-2-Acetylamino-4-methyl-pentanoic acid ((R)-3-benzyl-1-benzyloxy-2,5-dioxo-pyrrolidin-3-yl)-amide 
• 187345-49-9 (+)-(3R)-3-(N-acetyl-D-leucylamino)-3-benzyl-1-hydroxysuccinimide 

Relevant articles and documents

Synthesis of Phenylalanine-based Cyclic Acylated Enamino Ester Dipeptide Analogues: Inhibitors of α-Chymotrypsin. X-Ray Molecular Structure of (2'S,4'R)-4'-Benzyl-3'-benzyloxycarbonyl-5'-oxo-2'-phenyloxazolidin-4'-ylacetic Acid

Alkylation of the (S)-phenylalanine-derived syn-oxazolidinone 8 with BrCH2CO2CHPh2 gave compound 9, a key precursor to the β-keto ester 11 and the keto acid phosphorane 17.Compound 17 gave the enolactone 24 on heating and the bromo enolactone 19 and 20 on