16991-62-1

Basic information

• Product Name: 3α.6α-Dihydroxy-cholansaeuremethylester
• CAS NO: 16991-62-1
• Molecular Weight: 406.606
• Mol File: 16991-62-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3α.6α-Dihydroxy-cholansaeuremethylester(CAS DataBase Reference)
• NIST Chemistry Reference: 3α.6α-Dihydroxy-cholansaeuremethylester(16991-62-1)
• EPA Substance Registry System: 3α.6α-Dihydroxy-cholansaeuremethylester(16991-62-1)

Safety Data

• Hazardous Substances Data: 16991-62-1(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 

Downstream Products

• 911438-70-5 24,24-diphenyl-5α-cholane-3α,6α,24-triol 
• 55561-06-3 3α,6α-diacetoxy-24,24-diphenyl-5α-chola-20(22)ξ,23-diene of mp: 103 degree 
• 911438-77-2 3α,6α-diacetoxy-24,24-diphenyl-5α-chol-23-ene 
• 122678-13-1 24,24-diphenyl-5α-chola-20(22)ξ,23-diene-3α,6α-diol 
• 864-64-2 24,24-diphenyl-5α-chol-23-ene-3α,6α-diol 

Relevant articles and documents

Preparation method of muricholic acid

The invention relates to the technical field of drug synthesis, in particular to a preparation method of muricholic acid. According to the preparation method of the muricholic acid, 3[alpha], 6[alpha]-dyhydroxy-5[beta]-cholanic acid are used as raw materials for to be subjected to alkyl esterification, site-3 and site-6 selective oxidation is performed, a bromination reaction is performed, a substitution reaction is performed, site-6 reduction is performed, and hydrolysis is performed to obtain the muricholic acid. The muricholic acid is prepared by the synthetic route, namely 3[alpha], 6[beta], 7[beta]-trihydroxy-5[alpha]-cholanoic acid, a raw material source is wide, and sufficient supply is achieved; and the yield of the muricholic acid obtained by the steps is high and up to 24.5%, andthe muricholic acid is suitable for large-scale preparation and can provide data support and reference for subsequent related researches.