17000-57-6

Basic information

• Product Name: (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one
• CAS NO: 17000-57-6
• Molecular Formula: C₂₁H₃₂O₃
• Molecular Weight: 332.477
• Mol File: 17000-57-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 480.4°C at 760 mmHg
• Flash Point: 258.5°C
• Density: 1.15g/cm³
• Vapor Pressure: 3.01E-11mmHg at 25°C
• Refractive Index: 1.566
• CAS DataBase Reference: (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one(17000-57-6)
• EPA Substance Registry System: (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one(17000-57-6)

Safety Data

• Hazardous Substances Data: 17000-57-6(Hazardous Substances Data)

Usage

Description

(7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one is a synthetic chemical compound derived from the hormone testosterone, belonging to the class of androgens, which are male sex hormones. It features a molecular formula of C21H34O3 and is characterized by its specific configuration with two hydroxyl groups at positions 11 and 17, and two methyl groups at positions 7 and 17. (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one serves as a crucial intermediate in the synthesis of various steroid compounds due to its unique chemical structure and functional groups.

Uses

Used in Pharmaceutical Research and Development:
(7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one is utilized as an intermediate in the research and development of pharmaceuticals, particularly those targeting hormonal imbalances and related disorders. Its androgenic properties and structural features make it a valuable compound for creating new medications and therapies.
Used in Hormonal Imbalance Treatment:
In the medical field, (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one is used as a therapeutic agent for treating hormonal imbalances. Its androgen-like effects can help address conditions caused by insufficient or excessive levels of male sex hormones, such as hypogonadism or androgen deficiency syndrome.
Used in Steroid Synthesis:
As an important intermediate in the synthesis of steroid compounds, (7alpha,11beta,17beta)-11,17-dihydroxy-7,17-dimethylandrost-4-en-3-one is employed in the chemical industry for the production of various steroids. These synthesized steroids can be used in a range of applications, from pharmaceuticals to cosmetics and agricultural products.

Upstream product

• 1043-10-3 11β-hydroxy-17α-methyltestosterone 
• 17021-22-6 11β,17β-dihydroxy-17α-methyl-androsta-4,6-dien-3-one 
• 75-16-1 methylmagnesium bromide 

Relevant articles and documents

ANDROGEN AS A MALE CONTRACEPTIVE AND NON-CONTRACEPTIVE ANDROGEN REPLACEMENT

The present invention relates to methods of providing male contraception using a specified androgen without the need of a separate sterilizing agent. The invention also describes methods for non-contraceptive androgen replacement and devices useful for carrying out both processes.

Method for androgen supplementation

A particular group of androgens is not metabolized to their 5α-reduced form in the prostate and other tissues. Thus, administration of these compounds--testosterone derivatives with a non-hydrogen substituent in the 6α or 7α position--allows one to provide androgen supplementation therapy without stimulating abnormal prostate growth. A preferred compound for use in the invention is 7α-methyl-19-nortestosterone.