170033-58-6

Basic information

• Product Name: TERT-BUTYL-4-BENZYL-2(R)-METHYL-PIPERAZINECARBOXYLATE
• Synonyms: TERT-BUTYL-4-BENZYL-2(R)-METHYL-PIPERAZINECARBOXYLATE;(R)-tert-Butyl 4-benzyl-2-Methylpiperazine-1-carboxylate;R-1-Boc-2-methyl-4-(phenylmethyl)-piperazine
• CAS NO: 170033-58-6
• Molecular Formula: C₁₇H₂₆N₂O₂
• Molecular Weight: 290.4
• Mol File: 170033-58-6.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 371.545°C at 760 mmHg
• Flash Point: 178.504°C
• Appearance: /
• Density: 1.06g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.527
• CAS DataBase Reference: TERT-BUTYL-4-BENZYL-2(R)-METHYL-PIPERAZINECARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL-4-BENZYL-2(R)-METHYL-PIPERAZINECARBOXYLATE(170033-58-6)
• EPA Substance Registry System: TERT-BUTYL-4-BENZYL-2(R)-METHYL-PIPERAZINECARBOXYLATE(170033-58-6)

Safety Data

• Hazardous Substances Data: 170033-58-6(Hazardous Substances Data)

Usage

General Description

Tert-butyl-4-benzyl-2(R)-methyl-piperazinecarboxylate is a chemical compound with the molecular formula C22H32N2O2. It is a piperazine derivative containing a tert-butyl group, a benzyl group, and a methyl group. This chemical is often used as an intermediate in the synthesis of pharmaceutical compounds and agrochemicals. It may also have potential applications in medicinal chemistry and drug discovery due to its structural features and potential biological activities. Additionally, tert-butyl-4-benzyl-2(R)-methyl-piperazinecarboxylate may be used as a building block in organic synthesis for the creation of novel chemical entities with diverse properties and applications.

InChI:InChI=1/C17H26N2O2/c1-14-12-18(13-15-8-6-5-7-9-15)10-11-19(14)16(20)21-17(2,3)4/h5-9,14H,10-13H2,1-4H3/t14-/m1/s1

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 132871-11-5 (R)-3-Methyl-1-(phenylmethyl)piperazine 
• 153842-01-4 (R)-2-(2-Chloro-acetylamino)-propionic acid methyl ester 
• 132871-09-1 (R)-1-benzyl-3-methylpiperazine-2,5-dione 
• 170033-55-3 (R)-3-Methyl-1-(phenylmethyl)piperazin-2-one 
• 170033-65-5 (R)-2-Amino-N-benzyl-N-(2-hydroxy-ethyl)-propionamide 
• 170033-53-1 (R)-<2-<(2-Hydroxyethyl)(phenylmethyl)amino>-1-methyl-2-oxoethyl>carbamic acid 1,1-dimethylethyl ester 
• 104-63-2 N-Benzylethanolamine 
• 77-78-1 dimethyl sulfate 
• 57260-70-5 4-benzyl-piperazine-1-carboxylic acid tert-butyl ester 
• 74-88-4 methyl iodide 

Downstream Products

• 170033-47-3 (R)-tert-butyl 2-methylpiperazine-1-carboxylate 

Relevant articles and documents

Synthesis of Enantiopure Piperazines via Asymmetric Lithiation-Trapping of N-Boc Piperazines: Unexpected Role of the Electrophile and Distal N-Substituent

A new method for the synthesis of enantiopure α-substituted piperazines via direct functionalization of the intact piperazine ring is described. The approach utilizes the asymmetric lithiation-substitution of an α-methylbenzyl-functionalized N-Boc piperaz

A novel and facile method to synthesize (R)- and (S)-2-methylpiperazine

A concise and efficient synthesis of (R)- and (S)-2-methylpiperazine in only five steps from (D)- and (L)-alanine is described. The key step is reaction of benzylamine with a bifunctional molecule to build a six-membered ring.

Imidazo[1,5-A]quinolines for treatment of anxiety and sleep disorders

Imidazo[1,5-a]quinolines of formula (I) which are useful pharmaceutical agents for the treatment of anxiety, sleep disorders, panic states, convulsions and muscle disorders. STR1