17045-27-1 Usage
Description
(2-hydroxybenzyl)phosphonic acid is an organic compound that features a hydroxybenzyl group and a phosphonic acid group. The hydroxybenzyl group is characterized by a hydroxyl group attached to a benzene ring, while the phosphonic acid group consists of a phosphorus atom bonded to three oxygen atoms. (2-hydroxybenzyl)phosphonic acid is known for its strong bonding capabilities with metal ions, which makes it a versatile agent in various industrial applications.
Uses
Used in Water Treatment Industry:
(2-hydroxybenzyl)phosphonic acid is used as a chelating agent and corrosion inhibitor for preventing corrosion and scale formation in water treatment processes. Its strong bonding with metal ions contributes to its effectiveness in this application.
Used in Coordination Chemistry:
(2-hydroxybenzyl)phosphonic acid is used as a ligand in coordination chemistry, where it plays a crucial role in the formation of coordination compounds.
Used in Pharmaceutical Industry:
(2-hydroxybenzyl)phosphonic acid is used in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Organic Synthesis:
(2-hydroxybenzyl)phosphonic acid is also utilized in the synthesis of other organic compounds, showcasing its versatility in chemical reactions and applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 17045-27-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,0,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17045-27:
(7*1)+(6*7)+(5*0)+(4*4)+(3*5)+(2*2)+(1*7)=91
91 % 10 = 1
So 17045-27-1 is a valid CAS Registry Number.
17045-27-1Relevant articles and documents
Design and synthesis of amphiphilic 2-hydroxybenzylphosphonium salts with antimicrobial and antitumor dual action
Lyubina, Anna P.,Mironov, Vladimir F.,Pashirova, Tatiana N.,Sapunova, Anastasiia S.,Shaihutdinova, Zukhra M.,Tatarinov, Dmitry A.,Terekhova, Natalia V.,Voloshina, Alexandra D.,Zakharova, Lucia Ya.
, (2020/05/19)
Here we report the synthesis and biological evaluation of a series of new 2-hydroxybenzylphosphonium salts (QPS) with antimicrobial and antitumor dual action. The most active compounds exhibit antimicrobial activity at a micromolar level against Gram-positive bacteria Sa (ATCC 209p and clinical isolates), Bc (1–2 μM) and fungi Tm and Ca, and induced no notable hemolysis at MIC. The change in nature of substituents of the same length led to a drastic change of biological activity. Self-assembly behavior of the octadecyl and oleyl derivatives was studied. QPS demonstrated self-assembly within the micromolar range with the formation of nanosized aggregates capable of the solubilizing hydrophobic probe. The synthesized phosphonium salts were tested for cytotoxicity. The most potent salt was active against on M?Hela cell line with IC50 on the level of doxorubicin and good selectivity. According to the cytofluorimetry analysis, the salts induced mitochondria-dependent apoptosis.
