170456-83-4 Usage
Description
1-Tosyl-3-pyrrolidinol, with the CAS number 170456-83-4, is a white solid compound that is primarily utilized in the field of organic synthesis. It serves as a valuable intermediate in the creation of various organic compounds due to its unique chemical properties.
Uses
Used in Organic Synthesis:
1-Tosyl-3-pyrrolidinol is used as a synthetic intermediate for the production of a wide range of organic compounds. Its application in this field is due to its ability to facilitate the formation of complex molecules through various chemical reactions, making it a versatile building block in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
1-Tosyl-3-pyrrolidinol is used as a key component in the development of new pharmaceuticals. Its role in this industry is attributed to its potential to be incorporated into the molecular structure of various drugs, thereby contributing to their therapeutic properties and effectiveness in treating different medical conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 1-Tosyl-3-pyrrolidinol is used as a vital ingredient in the synthesis of novel agrochemicals. Its application in this industry is driven by its potential to enhance the performance of pesticides, herbicides, and other agricultural chemicals, ultimately leading to improved crop protection and yield.
Used in Specialty Chemicals:
1-Tosyl-3-pyrrolidinol is also employed in the production of specialty chemicals, which are tailored to meet the specific requirements of various industries. Its use in this area is due to its ability to impart unique properties to the final products, such as improved stability, reactivity, or selectivity, depending on the desired application.
Check Digit Verification of cas no
The CAS Registry Mumber 170456-83-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,0,4,5 and 6 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 170456-83:
(8*1)+(7*7)+(6*0)+(5*4)+(4*5)+(3*6)+(2*8)+(1*3)=134
134 % 10 = 4
So 170456-83-4 is a valid CAS Registry Number.
InChI:InChI=1/C11H15NO3S/c1-9-2-4-11(5-3-9)16(14,15)12-7-6-10(13)8-12/h2-5,10,13H,6-8H2,1H3
170456-83-4Relevant articles and documents
Proline-catalyzed sequential syn-Mannich and [4 + 1]-annulation cascade reactions to form densely functionalized pyrrolidines
Aher, Ravindra D.,Kumar, B. Senthil,Sudalai, Arumugam
, p. 2024 - 2031 (2015)
A highly efficient one-pot [4 + 1]-annulation process for the asymmetric synthesis of densely functionalized pyrrolidine derivatives is described. The in situ generated syn-Mannich adduct obtained via proline catalysis acts as a four-atom component, and Corey's sulfur ylide or ethyl bromoacetate acts as a one-atom carbon source to construct pyrrolidine units in a highly enantio- and diastereoselective manner.
A visible-light photoinduced charge-transfer complex promoted the ring opening of: N-alkyl-4-piperidinols
Du, Zhengyin,Fu, Ying,Huo, Congde,Shi, Chun-Zhao,Xu, Qin-Shan
supporting information, p. 2264 - 2269 (2020/04/21)
A visible-light photoinduced ring opening of N-alkyl-4-piperidinols under mild conditions has been achieved. The reaction sequence involves a visible-light-induced charge-transfer complex, which promoted the S-Cl bond cleavage of sulfonyl chlorides. The generated sulfonyl radical further reacts with N-alkyl-4-piperidinol cation radicals to achieve C-N and C-C bond cleavages to yield homoallylamine products.
Boron trifluoride etherate functioning as a fluorine source in an iodosobenzene-mediated intramolecular aminofluorination of homoallylic amines
Cui, Jian,Jia, Qun,Feng, Ruo-Zhu,Liu, Shan-Shan,He, Tian,Zhang, Chi
supporting information, p. 1442 - 1445 (2014/04/03)
A widely used Lewis acid BF3·Et2O was shown to be capable of acting as an efficient fluorinating agent in an intramolecular aminofluorination reaction of homoallylic amines to provide 3-fluoropyrrolidines mediated by a commercially available hypervalent iodine(III) reagent PhIO at room temperature. A mechanism involving a carbocation intermediate was proposed on the basis of several experimental evidence.
