170638-83-2

Basic information

• Product Name: 3-(3,4-Difluoro-phenyl)-cyclohex-2-enone
• CAS NO: 170638-83-2
• Molecular Weight: 208.208
• Mol File: 170638-83-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3,4-Difluoro-phenyl)-cyclohex-2-enone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3,4-Difluoro-phenyl)-cyclohex-2-enone(170638-83-2)
• EPA Substance Registry System: 3-(3,4-Difluoro-phenyl)-cyclohex-2-enone(170638-83-2)

Safety Data

• Hazardous Substances Data: 170638-83-2(Hazardous Substances Data)

Upstream product

• 348-61-8 1-bromo-3,4-difluorobenzene 
• 5323-87-5 3-Ethoxycyclohex-2-en-1-one 

Downstream Products

• 141106-30-1 8-(3,4-Difluoro-phenyl)-3,4-dihydro-2H-benzo[b]oxepin-5-one 
• 170639-05-1 [8-(3,4-Difluoro-phenyl)-2,3,4,5-tetrahydro-benzo[b]oxepin-5-yl]-heptyl-amine 

Relevant articles and documents

Synthesis and structure-activity relationships of new ACAT inhibitors

A series of heterocyclic ureas were synthesized and their ability to inhibit arterial and intestinal ACAT was assessed in animals.The structural modifications carried out in this series led to N2-(2,4-difluorophenyl)-N1-8-(4-fluorophenyl)-2,3,4,5-tetrahydro-1-benzoxepin-5-yl-N1-n-heptylurea 21, which proved to be very active on both the inhibition of aortic ACAT and the inhibition of rat cholesterol intestinal absorption, thus exhibiting a strong hypocholesterolemic effect po in rat (ED25 = 0.2 mg/kg). aortic ACAT / intestinal inhibition / benzoxepin / urea / cholesterol / hypocholesterolaemic activity