170874-98-3

Basic information

• Product Name: 4-Oxo-4-phenyl-2-thiophen-2-yl-butyric acid
• CAS NO: 170874-98-3
• Molecular Weight: 260.313
• Mol File: 170874-98-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Oxo-4-phenyl-2-thiophen-2-yl-butyric acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Oxo-4-phenyl-2-thiophen-2-yl-butyric acid(170874-98-3)
• EPA Substance Registry System: 4-Oxo-4-phenyl-2-thiophen-2-yl-butyric acid(170874-98-3)

Safety Data

• Hazardous Substances Data: 170874-98-3(Hazardous Substances Data)

Upstream product

• 188290-36-0 thiophene 
• 583-06-2 3-benzoylacrylic acid 

Relevant articles and documents

1,4-Arylation of β-aroylacrylic acids with thiophene and utilization of the products in synthesis of some heterocycles

β-Aroylacrylic acids react with thiophene in boiling benzene to give α-(2-thienyl)- β-aroylpropionic acids (1a-c). The reactions of 1c with hydrazine hydrate, hydroxylamine hydrochloride, semicarbazide hydrochloride, aromatic aldehydes, and acetic anhydride yield pyridazinone 2, oxazinone 3, semicarbazone 4, arylidene propionic acids (5a-c) and furanones (6a-c), respectively. The reactions of compound 6c with some nitrogen nucleophiles and aromatic hydrocarbons under Friedel Crafts' conditions have also been discussed.