170937-37-8Relevant articles and documents
Synthesis of 3-substituted pyrazole derivatives by mixed anhydride method and study of their antibacterial activities
Mishra, Sushanta Kumar,Majumdar, Poulomi,Behera, Rajani Kanta,Behera, Ajaya Kumar
supporting information, p. 32 - 41 (2013/11/06)
A convenient synthesis of 3-substituted pyrazole derivatives by a mixed anhydride method using i-butylchloroformate and N-methylmorpholine at-20 °C in tetrahydrofuran and study of in vitro antibacterial activities of the prepared compounds against Staphyl
Design, synthesis and biological evaluation of CB1 cannabinoid receptor ligands derived from the 1,5-diarylpyrazole scaffold
Tu, Guogang,Xiong, Fang,Huang, Huiming,Kuang, Binhai,Li, Shaohua
, p. 222 - 230 (2011/11/06)
The CB1 receptor belongs to the G-protein-coupled receptor superfamily. CB1 antagonism has been considered as a new therapeutic target for the treatment of obesity. In this study, we report the synthesis and in vitro binding affinity assay of some 1,5-dia
Synthesis and structure-activity relationship of novel diarylpyrazole imide analogues as CB1 cannabinoid receptor ligands
Song, Kwang-Seop,Kim, Min Ju,Seo, Hee Jeong,Lee, Sung-Han,Jung, Myung Eun,Kim, Soo-Un,Kim, Jeongmin,Lee, Jinhwa
experimental part, p. 3080 - 3092 (2009/09/25)
A myriad of research groups have been engaged in searching for novel CB1 receptor antagonists, since SR141716A (rimonabant), a CB1 receptor antagonist, was discovered for an obesity treatment. In this research, extended series, based on the 1,5-diarylpyra