170954-08-2Relevant articles and documents
Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds
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, (2008/06/13)
Quinolin-2-yl benzoic acid compounds which are useful as intermediates of quinoline compounds having angiotensin II antagonist activity prepared by decarboxylating 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds in which a carboxyl group bonded to a phenyl group may be esterified, while a carboxyl group bonded to a quinoline ring is not esterified, and both rings may have one or more substituents inert to the decarboxylation reaction.
Carbocyclic and nitrogen-containing fused CH-acids with an annelated indenyl fragment. Thermogravimetric and X-ray structural analysis of 6H-indenoquinoline
Pleshakov, V. G.,Akimov, V. M.,Nava, E. Huipe,Lindeman, S. V.,Struchkov, Yu. T.,et al.
, p. 682 - 688 (2007/10/02)
Based on thermogravimetric characteristics first obtained for the model 6H-indenoquinoline, the scheme of thermal conversions of this compound in the temperature range 20-700 deg C has been proposed, and the limit of its thermal stability (ca. 300 deg C) has been determined.This temperature is recommended as the optimum for synthesizing fused benzoaza(diaza)fluorenes.Based on the results of X-ray structural analysis, the molecules of the studied indenoquinoline form centrosymmetric pairs, which are arranged in (110) layers.The molecules are orientationally disordered self-association of these molecules is similar to the ?-? association of fused heterocyclic systems with ?-excessive and ?-deficient fragments.It has been suggested that interferon-inducing and antitumor compounds with an annelated indenyl fragment have a common mechanism of action according to the intercalation model of stacking structures. - Key words: CH-acids; 6H-indenoquinoline, heterogeneous catalytic dehydrogenation, thermogravimetric and X-ray structural analysis; interferon-inducing and antitumor intercalators; topological factor; stacking structures.