17099-07-9

Basic information

• Product Name: p-Chloro-N-(o-chlorobenzylidene)aniline
• Synonyms: p-Chloro-N-(o-chlorobenzylidene)aniline
• CAS NO: 17099-07-9
• Molecular Formula: C₁₃H₉Cl₂N
• Molecular Weight: 250.12
• Mol File: 17099-07-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 374.9 °C at 760 mmHg
• Flash Point: 180.5 °C
• Appearance: /
• Density: 1.2 g/cm³
• Vapor Pressure: 1.74E-05mmHg at 25°C
• Refractive Index: 1.583
• CAS DataBase Reference: p-Chloro-N-(o-chlorobenzylidene)aniline(CAS DataBase Reference)
• NIST Chemistry Reference: p-Chloro-N-(o-chlorobenzylidene)aniline(17099-07-9)
• EPA Substance Registry System: p-Chloro-N-(o-chlorobenzylidene)aniline(17099-07-9)

Safety Data

• Hazardous Substances Data: 17099-07-9(Hazardous Substances Data)

Usage

General Description

p-Chloro-N-(o-chlorobenzylidene)aniline is a chemical compound with the formula C13H9Cl2N. It is a yellowish-brown crystalline solid with a molecular weight of 247.13 g/mol. p-Chloro-N-(o-chlorobenzylidene)aniline is commonly used as a dye intermediate and is also known for its antibacterial and antifungal properties. It is primarily used in the production of azo dyes, which are extensively used in the textile industry. Additionally, it has potential applications in the field of medicine for its antimicrobial properties. However, it is important to handle this compound with caution as it can be harmful if ingested or inhaled, and may cause skin irritation upon contact.

InChI:InChI=1/C13H9Cl2N/c14-11-5-7-12(8-6-11)16-9-10-3-1-2-4-13(10)15/h1-9H/b16-9+

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 106-47-8 4-chloro-aniline 
• 878561-50-3 C-(2-chlorophenyl)-N-(4-chlorophenyl)nitrone 
• 823-86-9 N-(4-chlorophenyl)hydroxylamine 

Downstream Products

• 102912-63-0 2-(2-chloro-styryl)-naphtho[1,2-d]thiazole 
• 107624-75-9 N-(o-chlorobenzyl)-p-chloroaniline 
• 927194-63-6 ethyl 5-(2-chlorophenyl)-1-(4-chlorophenyl)-3-hydroxy-2-oxo-2,5-dihydro-1H-pyrrole-4-carboxylate 

Relevant articles and documents

Development of novel vitamin D receptor-coactivator inhibitors

Nuclear receptor coregulators are master regulators of transcription and selectively interact with the vitamin D receptor (VDR) to modulate cell differentiation, cell proliferation, and calcium homeostasis. Herein, we report the syntheses and evaluation of highly potent and selective VDR-coactivator inhibitors based on a recently identified 3-indolylmethanamine scaffold. The most active compound, PS121912, selectively inhibited VDR-mediated transcription among eight other nuclear receptors tested. PS121912 is also selectively disrupting the binding between VDR and the third nuclear receptor interaction domain of the coactivator SRC2. Genetic studies revealed that PS121912 behaves like a VDR antagonist by repressing 1,25-(OH)2D3 activated gene transcription. In addition, PS121912 induced apoptosis in HL-60.

CANNABINOID RECEPTOR LIGANDS AND USES THEREOF

Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein.

Polarographic investigations on azomethines: Benzal-p-chloranilines in alkaline medium and effect of substituents on half-wave potentials

Polarographic behavior of twenty-four substituted benzal-p-chloranilines has been investigated in 50percent methanol-water medium in alkaline pH range.The experimental conditions for the study were so designed that no appreciable hydrolysis of the Schiff