170999-47-0

Basic information

• Product Name: Di-imidazol-1-yl-phosphinic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester
• CAS NO: 170999-47-0
• Molecular Weight: 724.71
• Mol File: 170999-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Di-imidazol-1-yl-phosphinic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Di-imidazol-1-yl-phosphinic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(170999-47-0)
• EPA Substance Registry System: Di-imidazol-1-yl-phosphinic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethyl ester(170999-47-0)

Safety Data

• Hazardous Substances Data: 170999-47-0(Hazardous Substances Data)

Upstream product

• 16062-77-4 phosphorotriimidazolide 
• 76054-81-4 3'-O-(4,4'-dimethoxytrityl)thymidine 

Downstream Products

• 170999-48-1 C₂₄H₂₇N₂O₁₂PS₂ 
• 170999-49-2 Toluene-4-sulfonic acid (4aR,6R,7aS)-6-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-oxo-tetrahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-2-yl ester 

Relevant articles and documents

New General Synthesis of Organophosphorus P-F Compounds via Reaction of Azolides of Phosphorus Acids with Acyl Fluorides: Novel Route to 2-Deoxynucleosidyl Phosphorofluoridates and Phosphorodifluoridates

Tetra- and tri-coordinate P-N-imidazole derivatives and their structural analogous react smoothly with acyl fluorides to give the corresponding P-F compounds an almost quantitative yield.This method has been successfully applied to produce 2-deoxynucleosidyl phosphorofluoridates and phosphorodifluoridates.